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“这种(暴露前预防)从何而来?”非裔美国母女对青少年暴露前预防(PrEP)使用及临床试验参与的看法

"Where Did This [PrEP] Come From?" African American Mother/Daughter Perceptions Related to Adolescent Preexposure Prophylaxis (PrEP) Utilization and Clinical Trial Participation.

作者信息

Fletcher Faith E, Fisher Celia, Buchberg Meredith K, Floyd Brenikki, Hotton Anna, Ehioba Angelica, Donenberg Geri

机构信息

1 University of Alabama at Birmingham, USA.

2 Fordham University, Bronx, NY, USA.

出版信息

J Empir Res Hum Res Ethics. 2018 Apr;13(2):173-184. doi: 10.1177/1556264618755919. Epub 2018 Feb 22.

DOI:10.1177/1556264618755919
PMID:29471706
Abstract

Despite the demonstrated effectiveness of preexposure prophylaxis (PrEP) to reduce incident HIV infections, PrEP's potential as an HIV prevention strategy for adolescent populations is unknown. This study assessed perceptions of adolescent PrEP use and clinical trial participation among African American women and their adolescent daughters. We conducted focus group discussions with 15 African American mother/daughter pairs ( N = 30). Findings suggest a general lack of PrEP awareness, favorable attitudes toward adolescent PrEP use, altruistic attitudes regarding research participation among daughters, and less favorable attitudes toward adolescent clinical trial participation among mothers. Study findings have the potential to inform strategies that provide equitable access to HIV scientific advances among African American women and girls and promote informed parent-child research decision making.

摘要

尽管暴露前预防(PrEP)已被证明能有效减少新发艾滋病毒感染,但PrEP作为青少年人群艾滋病毒预防策略的潜力尚不清楚。本研究评估了非裔美国女性及其青春期女儿对青少年使用PrEP和参与临床试验的看法。我们对15对非裔美国母女(N = 30)进行了焦点小组讨论。研究结果表明,普遍缺乏对PrEP的认识,对青少年使用PrEP持积极态度,女儿们对参与研究持利他态度,而母亲们对青少年参与临床试验的态度则不太积极。研究结果有可能为制定相关策略提供参考,这些策略能让非裔美国妇女和女孩平等地接触到艾滋病毒防治方面的科学进展,并促进明智的亲子研究决策。

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