Khan Shahid Ullah, Anjum Syed Ishtiaq, Rahman Khaista, Ansari Mohammad Javed, Khan Wasim Ullah, Kamal Sajid, Khattak Baharullah, Muhammad Ali, Khan Hikmat Ullah
Huazhong Agricultural University, Wuhan 430070, PR China.
Department of Zoology, Kohat University of Science and Technology, Kohat 26000, Pakistan.
Saudi J Biol Sci. 2018 Feb;25(2):320-325. doi: 10.1016/j.sjbs.2017.08.004. Epub 2017 Aug 16.
Honey is a natural food item produced by honey bees. Ancient civilizations considered honey as a God gifted prestigious product. Therefore, a huge literature is available regarding honey importance in almost all religions. Physically, honey is a viscous and jelly material having no specific color. Chemically, honey is a complex blend of many organic and inorganic compounds such as sugars, proteins, organic acids, pigments, minerals, and many other elements. Honey use as a therapeutic agent is as old as human civilization itself. Prior to the appearance of present day drugs, honey was conventionally used for treating many diseases. At this instant, the modern research has proven the medicinal importance of honey. It has broad spectrum anti-biotic, anti-viral and anti-fungal activities. Honey prevents and kills microbes through different mechanism such as elevated pH and enzyme activities. Till now, no synthetic compound that works as anti-bacterial, anti-viral and anti-fungal drugs has been reported in honey yet it works against bacteria, viruses and fungi while no anti-protozoal activity has been reported. Potent anti-oxidant, anti-inflammatory and anti-cancerous activities of honey have been reported. Honey is not only significant as anti-inflammatory drug that relieve inflammation but also protect liver by degenerative effects of synthetic anti-inflammatory drugs. This article reviews physico-chemical properties, traditional use of honey as medicine and mechanism of action of honey in the light of modern scientific medicinal knowledge.
蜂蜜是蜜蜂生产的一种天然食品。古代文明将蜂蜜视为上帝赐予的珍贵产品。因此,几乎在所有宗教中都有大量关于蜂蜜重要性的文献。从物理性质上讲,蜂蜜是一种粘性的胶状物质,没有特定颜色。从化学角度看,蜂蜜是多种有机和无机化合物的复杂混合物,如糖、蛋白质、有机酸、色素、矿物质和许多其他元素。蜂蜜作为一种治疗剂的使用与人类文明本身一样古老。在现代药物出现之前,蜂蜜传统上被用于治疗多种疾病。如今,现代研究已经证实了蜂蜜的药用价值。它具有广谱的抗菌、抗病毒和抗真菌活性。蜂蜜通过不同机制预防和杀死微生物,如提高pH值和酶活性。到目前为止,蜂蜜中尚未报道有作为抗菌、抗病毒和抗真菌药物起作用的合成化合物,但它对细菌、病毒和真菌有效,而尚未报道有抗原生动物活性。蜂蜜还具有强大的抗氧化、抗炎和抗癌活性。蜂蜜不仅作为缓解炎症的抗炎药物具有重要意义,还能通过合成抗炎药物的退行性作用来保护肝脏。本文根据现代科学医学知识,综述了蜂蜜的物理化学性质、作为药物的传统用途及其作用机制。