State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.
School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.
Appl Microbiol Biotechnol. 2018 Apr;102(8):3701-3709. doi: 10.1007/s00253-018-8855-2. Epub 2018 Mar 7.
Increasing evidence suggests that the intestinal microbiota is closely correlated with the host's health status. Thus, a serious disturbance that disrupts the stability of the intestinal microecosystem could cause host disease. Shrimps are one of the most important products among fishery trading commodities. However, digestive system diseases, such as white feces syndrome (WFS), frequently occur in shrimp culture and have led to enormous economic losses across the world. The WFS occurrences are unclear. Here, we compared intestinal bacterial communities of WFS shrimp and healthy shrimp. Intestinal bacterial communities of WFS shrimp exhibited less diversity but were more heterogeneous than those of healthy shrimp. The intestinal bacterial communities were significantly different between WFS shrimp and healthy shrimp; compared with healthy shrimp, in WFS shrimp, Candidatus Bacilloplasma and Phascolarctobacterium were overrepresented, whereas Paracoccus and Lactococcus were underrepresented. PICRUSt functional predictions indicated that the relative abundances of genes involved in energy metabolism and genetic information processing were significantly greater in WFS shrimp. Collectively, we found that the composition and predicted functions of the intestinal bacterial community were markedly shifted by WFS. Significant increases in Candidatus Bacilloplasma and Phascolarctobacterium and decreases in Paracoccus and Lactococcus may contribute to WFS in shrimp.
越来越多的证据表明，肠道微生物群与宿主的健康状况密切相关。因此，严重扰乱肠道微生态系统稳定性的干扰可能导致宿主疾病。虾是渔业贸易商品中最重要的产品之一。然而，消化系统疾病，如白便综合征（WFS），在虾类养殖中经常发生，并在世界范围内造成了巨大的经济损失。WFS 的发生情况尚不清楚。在这里，我们比较了 WFS 虾和健康虾的肠道细菌群落。WFS 虾的肠道细菌群落多样性较低，但异质性较高。WFS 虾和健康虾的肠道细菌群落有显著差异；与健康虾相比，在 WFS 虾中，Candidatus Bacilloplasma 和 Phascolarctobacterium 过度表达，而 Paracoccus 和 Lactococcus 则表达不足。PICRUSt 功能预测表明，WFS 虾中与能量代谢和遗传信息处理相关的基因的相对丰度显著增加。总的来说，我们发现 WFS 显著改变了肠道细菌群落的组成和预测功能。Candidatus Bacilloplasma 和 Phascolarctobacterium 的显著增加和 Paracoccus 和 Lactococcus 的减少可能导致虾类的 WFS。
