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The Papillomavirus Episteme: a major update to the papillomavirus sequence database.乳头瘤病毒知识数据库:乳头瘤病毒序列数据库的重大更新。
Nucleic Acids Res. 2017 Jan 4;45(D1):D499-D506. doi: 10.1093/nar/gkw879. Epub 2016 Oct 5.
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Biological agents.生物制剂
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Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments.基于 189 种 HPV 型别对乳头瘤病毒(PVs)的分类以及分类学修订建议。
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E7 oncoprotein of novel human papillomavirus type 108 lacking the E6 gene induces dysplasia in organotypic keratinocyte cultures.缺乏E6基因的新型人乳头瘤病毒108型E7癌蛋白在器官型角质形成细胞培养中诱导发育异常。
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Human papillomavirus (HPV) types 101 and 103 isolated from cervicovaginal cells lack an E6 open reading frame (ORF) and are related to gamma-papillomaviruses.从宫颈阴道细胞中分离出的人乳头瘤病毒101型和103型缺乏E6开放阅读框(ORF),且与γ-乳头瘤病毒相关。
Virology. 2007 Apr 10;360(2):447-53. doi: 10.1016/j.virol.2006.10.022. Epub 2006 Nov 22.
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Classification of papillomaviruses.乳头瘤病毒的分类
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A sequence-independent strategy for detection and cloning of circular DNA virus genomes by using multiply primed rolling-circle amplification.一种通过多重引物滚环扩增检测和克隆环状DNA病毒基因组的不依赖序列的策略。
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从卢森堡一份宫颈拭子中分离出的新型人γ乳头瘤病毒的全基因组序列

Complete Genome Sequence of a Novel Human Gammapapillomavirus Isolated from a Cervical Swab in Luxembourg.

作者信息

Latsuzbaia Ardashel, Arbyn Marc, Dutta Sankhadeep, Fischer Marc, Gheit Tarik, Tapp Jessica, Tommasino Massimo, Weyers Steven, Mossong Joël

机构信息

Epidemiology and Microbial Genomics, Laboratoire National de Santé, Dudelange, Luxembourg

Unit of Cancer Epidemiology, Belgian Cancer Centre Scientific Institute of Public Health, Brussels, Belgium.

出版信息

Genome Announc. 2018 Mar 15;6(11):e00114-18. doi: 10.1128/genomeA.00114-18.

DOI:10.1128/genomeA.00114-18
PMID:29545294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5854775/
Abstract

A novel human papillomavirus genotype was detected in a cervical swab specimen by next-generation sequencing after rolling circular amplification. It was fully cloned and characterized. The L1 open reading frame showed 77% nucleotide similarity with the closest genotype, HPV101, belonging to the gamma-6 species.

摘要

通过滚环扩增后的二代测序在宫颈拭子标本中检测到一种新型人乳头瘤病毒基因型。对其进行了全克隆和特征分析。L1开放阅读框与最接近的基因型HPV101(属于γ-6种)显示出77%的核苷酸相似性。