Latsuzbaia Ardashel, Arbyn Marc, Dutta Sankhadeep, Fischer Marc, Gheit Tarik, Tapp Jessica, Tommasino Massimo, Weyers Steven, Mossong Joël
Epidemiology and Microbial Genomics, Laboratoire National de Santé, Dudelange, Luxembourg
Unit of Cancer Epidemiology, Belgian Cancer Centre Scientific Institute of Public Health, Brussels, Belgium.
Genome Announc. 2018 Mar 15;6(11):e00114-18. doi: 10.1128/genomeA.00114-18.
A novel human papillomavirus genotype was detected in a cervical swab specimen by next-generation sequencing after rolling circular amplification. It was fully cloned and characterized. The L1 open reading frame showed 77% nucleotide similarity with the closest genotype, HPV101, belonging to the gamma-6 species.
通过滚环扩增后的二代测序在宫颈拭子标本中检测到一种新型人乳头瘤病毒基因型。对其进行了全克隆和特征分析。L1开放阅读框与最接近的基因型HPV101(属于γ-6种)显示出77%的核苷酸相似性。