Lam Alfred K, Leung Melissa
Cancer Molecular Pathology of School of Medicine, Griffith University, Gold Coast, Australia.
Methods Mol Biol. 2018;1756:135-142. doi: 10.1007/978-1-4939-7734-5_12.
Whole-slide imaging revolutionizes the field of pathology especially in the areas of facilitation of research, long-term storages, exchange of information, and image analysis. In this process, a scanning equipment (scanner) scans the whole glass slide into a digital file. In research in esophageal adenocarcinoma or other cancers, whole-slide imaging could help in production of high-resolution images for studying and sharing of research information, assessment of tissue microarray slides as well as allowing digital image analysis of the tissue information such as level of staining (e.g., HER2) in a more efficient and objective manner. In this chapter, we will elaborate the concepts, advantages, barriers, and the operations of whole-slide imaging scanning.
全玻片成像彻底改变了病理学领域，尤其是在促进研究、长期存储、信息交换和图像分析等方面。在此过程中，扫描设备（扫描仪）将整个玻璃玻片扫描成数字文件。在食管腺癌或其他癌症的研究中，全玻片成像有助于生成高分辨率图像以用于研究和研究信息共享、评估组织微阵列玻片，还能更高效、客观地对组织信息进行数字图像分析，如染色水平（如HER2）。在本章中，我们将详细阐述全玻片成像扫描的概念、优势、障碍及操作。
