食管鳞状细胞癌的全 slides 成像。

Whole-Slide Imaging of Esophageal Squamous Cell Carcinoma.

机构信息

Cancer Molecular Pathology, School of Medicine, Griffith University, Gold Coast, Queensland, Australia.

Cancer Molecular Pathology of School of Medicine, Griffith University, Gold Coast, Queensland, Australia.

出版信息

Methods Mol Biol. 2020;2129:107-117. doi: 10.1007/978-1-0716-0377-2_9.

DOI:10.1007/978-1-0716-0377-2_9

PMID:32056173

Abstract

Whole-slide imaging (WSI) contributes to medical education, collaboration, quality assurance, examination, and consultation in pathology. The images obtained from WSI are of high quality and could be stored indefinitely. In research involving esophageal squamous cell carcinoma, the combination of WSI and image processing program allows effective interpretations of expressions of various immunomarkers related to pathogenesis, prognosis, and response to therapy in tissue microarray sections. The operation and basic principles of whole-slide imaging of esophageal squamous cell carcinoma are also presented. Common use of WSI will occur with modifications of the whole-slide imaging scanners to adapt to the workflows in diagnostic and research laboratories.

摘要

全玻片成像（WSI）有助于病理学中的医学教育、协作、质量保证、检查和咨询。从 WSI 获得的图像质量很高，可以无限期存储。在涉及食管鳞状细胞癌的研究中，WSI 与图像处理程序的结合允许对组织微阵列切片中与发病机制、预后和治疗反应相关的各种免疫标志物的表达进行有效解读。还介绍了食管鳞状细胞癌全玻片成像的操作和基本原则。随着全玻片成像扫描仪的修改以适应诊断和研究实验室的工作流程，WSI 将得到广泛应用。