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肝切除术中手术应激的免疫学评估

Immunological Evaluation of Surgical Stress in Liver Resections.

作者信息

Munteanu Alexandru, Samasca Gabriel, Lupan Iulia, Iancu Cornel

机构信息

Department of Surgery, "Octavian Fodor" Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Romania.

Department of Immunology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

出版信息

Maedica (Bucur). 2017 Dec;12(4):289-292.

Abstract

Surgery has its origins in caring for patients suffering from injury or infection. In the last decade, a huge amount of published data has been describing a wide range of conditions resulting from trauma or infection, from minor, local reactions to a surgical operation and leading to a systemic stress response, systemic inflammatory response and finally to multiple organ failure. Our aim was to highlight the main immunological aspects of liver resections. There are many types of liver resections, ranging from small, isolated resections for benign diseases (e.g., small cysts or angyoma) to segmentectomies, bi- or trisegmentectomies to hepatectomies in the end. Patients undergoing such resections are subjected to a large amount of surgical stress and in some cases, postoperative complications ranging from light to severe. The main links between immunology and liver resections is surgical stress that can be evaluated through various immunological methods, which will be presented in this article.

摘要

外科手术起源于对受伤或感染患者的护理。在过去十年中,大量已发表的数据描述了由创伤或感染导致的广泛病症,从外科手术引起的轻微局部反应,到全身应激反应、全身炎症反应,最终发展为多器官功能衰竭。我们的目的是突出肝切除术的主要免疫学方面。肝切除术有多种类型,从针对良性疾病的小范围孤立性切除(如小囊肿或血管瘤),到肝段切除术、双段或三段肝段切除术,直至最终的肝切除术。接受此类切除术的患者会承受大量手术应激,在某些情况下还会出现从轻度到重度的术后并发症。免疫学与肝切除术之间的主要联系在于手术应激,可通过各种免疫学方法对其进行评估,本文将对此进行阐述。

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本文引用的文献

1
The role of serum interleukin-8 in hepatic resections.血清白细胞介素-8 在肝切除术中的作用。
Surg Today. 2010 Jun;40(6):543-8. doi: 10.1007/s00595-008-4086-y. Epub 2010 May 23.

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