Roosta Sajjad, Kharadmand Mina, Teymoori Farshad, Birjandi Mehdi, Adine Ahmad, Falahi Ebrahim
Student Research Committee, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Islamic Republic of Iran.
School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Islamic Republic of Iran.
Diabetes Metab Syndr. 2018 Jul;12(4):537-541. doi: 10.1016/j.dsx.2018.03.022. Epub 2018 Mar 27.
The aim of this study was to investigate effect of vitamin D supplementation on anthropometric indices among women with overweight and obesity.
This double blind randomize clinical trial was conducted on 66 overweight and obese women. Those in intervention group received oral supplement of vitamin D 50,000 IU (1250 mcg) per 25 day and in control group participants received placebo for 3 months. Anthropometric indices were measured before and after 3 months intervention. Before the intervention a 24-h dietary recall (3 days) were used to assess dietary intake of individuals. Independent t test and multivariate repeated measure were used to data analysis.
The mean difference of anthropometric indices, serum calcium, 25 (OH) D and serum PTH between the intervention and control groups were significant (P < 0/05). However, no significant differences in serum phosphorus between the intervention and control groups were seen.
Supplementation with vitamin D 50 μg for each day for 3 months resulted in a significant reduction in anthropometric indices in women with obesity and overweight with normal primary 25(OH) D serum levels.
本研究旨在探讨补充维生素D对超重和肥胖女性人体测量指标的影响。
对66名超重和肥胖女性进行了这项双盲随机临床试验。干预组每25天口服50000国际单位（1250微克）维生素D，对照组参与者服用安慰剂，为期3个月。在干预前后测量人体测量指标。在干预前，采用24小时饮食回顾法（3天）评估个体的饮食摄入量。采用独立t检验和多变量重复测量进行数据分析。
干预组和对照组之间人体测量指标、血清钙、25（OH）D和血清甲状旁腺激素的平均差异具有统计学意义（P<0.05）。然而，干预组和对照组之间血清磷没有显著差异。
对于原发性25（OH）D血清水平正常的肥胖和超重女性，每天补充50微克维生素D，持续3个月，可显著降低人体测量指标。
