Golicki Dominik, Niewada Maciej, Hout Ben van, Janssen M F, Pickard A Simon
Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Warsaw, Poland.
Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Warsaw, Poland.
Value Health Reg Issues. 2014 Sep;4:19-23. doi: 10.1016/j.vhri.2014.06.001. Epub 2014 Jul 8.
To estimate an interim five-level EuroQol five-dimensional (EQ-5D-5L) value set for Poland on the basis of the crosswalk methodology developed by the EuroQol Group.
On the basis of data from 3691 respondents from six European countries, the EuroQol Group has developed a method of obtaining interim value sets for the EQ-5D-5L by means of mapping to the available three-level EuroQol five-dimensional (EQ-5D-3L) value sets ("crosswalk" methodology). A significant part of the data in this study came from Polish respondents (n = 972; 26.3%). Poland is the first Central European country with EQ-5D-3L time trade-off-based social value set published. To obtain an interim EQ-5D-5L value set, we applied the crosswalk methodology to the Polish EQ-5D-3L value set.
Estimated Polish values for 3125 EQ-5D-5L health states are presented. Both EQ-5D-5L and EQ-5D-3L value sets have the same range (from -0.523 to 1.000), but different means (0.448 vs. 0.380) and medians (0.483 vs. 0.403), respectively. Proportionately fewer states worse than dead were observed in the EQ-5D-5L (5.4%) value set than in the EQ-5D-3L (13.2%) value set.
The crosswalk-based value set is available for use in EQ-5D-5L studies in Poland to calculate health state utilities. It should be considered an interim value set until values based on preferences elicited directly from a sample representative of the Polish general population become available. This study helps users of the crosswalk algorithm understand the properties of the EQ-5D-5L values generated using this method, in comparison to EQ-5D-3L values obtained with the Polish time trade-off value set. It is likely that similar results would be observed for values sets in other countries because the same crosswalk methodology applies across all countries.
基于欧洲生活质量研究组（EuroQol Group）开发的交叉法，估算波兰的临时五级欧洲生活质量五维度（EQ-5D-5L）值集。
欧洲生活质量研究组依据来自六个欧洲国家3691名受访者的数据，开发了一种通过映射到可用的三级欧洲生活质量五维度（EQ-5D-3L）值集来获取EQ-5D-5L临时值集的方法（“交叉”法）。本研究中的很大一部分数据来自波兰受访者（n = 972；26.3%）。波兰是首个发布基于EQ-5D-3L时间权衡法的社会价值集的中欧国家。为获取临时EQ-5D-5L值集，我们将交叉法应用于波兰的EQ-5D-3L值集。
给出了3125种EQ-5D-5L健康状态的估算波兰值。EQ-5D-5L和EQ-5D-3L值集范围相同（从-0.523至1.000），但均值不同（分别为0.448和0.380），中位数也不同（分别为0.483和0.403）。在EQ-5D-5L值集中观察到比死亡状态更差的状态比例（5.4%）低于EQ-5D-3L值集（13.2%）。
基于交叉法的值集可用于波兰的EQ-5D-5L研究以计算健康状态效用值。在基于直接从波兰普通人群代表性样本中得出的偏好值可用之前，应将其视为临时值集。本研究有助于交叉算法的使用者了解使用此方法生成的EQ-5D-5L值与通过波兰时间权衡值集获得的EQ-5D-3L值相比的特性。由于相同的交叉法适用于所有国家，其他国家的值集可能会观察到类似结果。
