Friesen Lynn Roosa, Williams Karen B
Director of Corporate Clinical Research, Department of Research and Graduate Programs, University of Missouri - Kansas City School of Dentistry, 650 E. 25th St, Kansas City, MO 64108, United States.
Department of Biomedical and Health Informatics, University of Missouri- Kansas City School of Medicine, 1000 E. 24th St, Kansas City, MO 64108, United States.
Contemp Clin Trials Commun. 2016 Jan 12;2:85-90. doi: 10.1016/j.conctc.2015.12.011. eCollection 2016 Apr 15.
This study examined attitudes about research, knowledge of the research process, reasons for and satisfaction with participation in a dental clinical trial as a function of demographic characteristics.
180 adults were invited to complete a 47-item survey at the completion of a 10-week dental product study at a Midwestern academic dental center. Seven demographic items included gender, race/ethnicity, age, education, household income, location of usual dental care, and dental insurance. Forty items assessed: attitudes about research; knowledge of the research process; perception of the study team; perceived risks/benefits; health perceptions; and general satisfaction with the study.
176 participants completed the questionnaire for a 98% response rate. African Americans were more likely to attribute Fate/God as more important to their health and their willingness to participate in research than whites, and more likely to report non-supportive social norms when compared to whites and other groups. Individuals in the 45-59 age group were less likely to attribute financial reimbursement as a motivator for their participation in research compared to all other age groups. Individuals with less education rated Fate/God attitudes as important to their research participation, reported lower autonomy for participation, and reported less supportive social norms compared to those with some college education. Participants in the four income categories showed significant differences in reasons for participation and desire for free care.
Motivations for participation of a Midwestern population of research subjects are dependent on age, ethnicity, belief in Fate/God, education, social norms and income.
本研究考察了作为人口统计学特征函数的对研究的态度、对研究过程的了解、参与牙科临床试验的原因及满意度。
在中西部一所学术性牙科中心完成一项为期10周的牙科产品研究后，邀请180名成年人完成一份包含47个条目的调查问卷。七个人口统计学条目包括性别、种族/族裔、年龄、教育程度、家庭收入、常规牙科护理地点及牙科保险。40个条目评估了：对研究的态度；对研究过程的了解；对研究团队的认知；感知到的风险/益处；健康认知；以及对该研究的总体满意度。
176名参与者完成了问卷，回复率为98%。与白人相比，非裔美国人更倾向于将命运/上帝视为对其健康更重要的因素以及他们参与研究的意愿，并且与白人和其他群体相比，更有可能报告不支持的社会规范。与所有其他年龄组相比，45 - 59岁年龄组的个体不太可能将经济补偿作为其参与研究的动机。与接受过一些大学教育的人相比，教育程度较低的个体认为命运/上帝态度对其参与研究很重要，报告参与的自主性较低，并且报告的社会规范支持度较低。四个收入类别的参与者在参与原因和对免费护理的渴望方面存在显著差异。
中西部研究对象群体参与研究的动机取决于年龄、种族、对命运/上帝的信仰、教育程度、社会规范和收入。
