发育中人类大脑的葡萄糖需求
Glucose Requirements of the Developing Human Brain.
作者信息
Goyal Manu S, Raichle Marcus E
机构信息
Neuroimaging Laboratories, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO.
出版信息
J Pediatr Gastroenterol Nutr. 2018 Jun;66 Suppl 3(Suppl 3):S46-S49. doi: 10.1097/MPG.0000000000001875.
Abstract
Adequate nutrition is critical for human brain development, which depends particularly upon glucose. The adult human brain accounts for 20% to 25% of total body resting glucose consumption, and studies indicate that the developing brain requires an even greater percentage of glucose. Here we critically review the currently available data on glucose requirements for early childhood brain development. Implications of these findings are then discussed in the context of childhood malnutrition and future areas of investigation.
摘要
充足的营养对人类大脑发育至关重要，大脑发育尤其依赖葡萄糖。成人大脑的静息葡萄糖消耗量占全身的20%至25%，研究表明，发育中的大脑需要更高比例的葡萄糖。在此，我们严格审查了目前关于幼儿大脑发育葡萄糖需求量的现有数据。然后在儿童营养不良的背景下讨论了这些发现的意义以及未来的研究领域。
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