婆罗洲软珊瑚 sp. 中具有抗真菌活性的新型海松烷二萜类化合物。
New cembrane-type diterpenoids from Bornean soft coral sp. with antifungal activity against .
机构信息
Laboratory of Natural Products Chemistry, Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah , Kota Kinabalu , Malaysia.
出版信息
Nat Prod Res. 2019 Dec;33(23):3343-3349. doi: 10.1080/14786419.2018.1475387. Epub 2018 May 17.
Three new cembrane diterpenes, nephthecrassocolides A-B (-) and 6-acetoxy nephthenol acetate () along with three known compounds, 6-acetoxy-7,8-epoxy nephthenol acetate (), epoxy nephthenol acetate () and nephthenol () were isolated from one population of sp. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds - were evaluated.
从 sp. 的一个种群中分离得到了三个新的海松烷二萜类化合物，nephthecrassocolides A-B (-) 和 6-乙酰氧基 nephthenol 乙酸酯 ()，以及三个已知化合物，6-乙酰氧基-7,8-环氧 nephthenol 乙酸酯 ()、环氧 nephthenol 乙酸酯 ()和 nephthenol ()。基于光谱数据分析确定了它们的结构，并评估了化合物 - 的抗真菌活性。
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