Kamada Takashi, Phan Chin-Soon, Tin Hoe-Seng, Vairappan Charles Santhanaraju, Muhammad Tengku Sifzizul Tengku
Nat Prod Commun. 2016 Aug;11(8):1077-1078.
One new cembrane diterpene, 16-hydroxycembra-1,3,7,11-tetraene (1), along with three known compounds, 15-hydroxycembra-1,3,7,11-tetraene (2), sarcophine (3) and sarcophytoxide (4) were isolated from Sarcophyton sp. collected from Karah Island, Terengganu, West Malaysia. Their structures were elucidated based on spectroscopic data. Activities of these compounds against antibacterial resistant clinical bacteria are reported. Only 1 exhibited inhibition against Staphylococcus aureus.
从马来西亚丁加奴州瓜拉岛采集的肉芝软珊瑚中分离得到一个新的西松烷二萜，16-羟基西松-1,3,7,11-四烯（1），以及三个已知化合物，15-羟基西松-1,3,7,11-四烯（2）、肉芝碱（3）和肉芝毒素（4）。根据光谱数据阐明了它们的结构。报道了这些化合物对耐抗菌临床细菌的活性。只有1对金黄色葡萄球菌有抑制作用。
