Matsuzaki Juntaro, Suzuki Hidekazu, Togawa Koji, Yamane Tsuyoshi, Mori Hideki, Komori Takahiro, Masaoka Tatsuhiro, Kanai Takanori
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.
United European Gastroenterol J. 2018 Apr;6(3):398-406. doi: 10.1177/2050640617726466. Epub 2017 Aug 7.
Impaired sleep quality is common, and can reduce work productivity in patients with functional dyspepsia (FD).
The objective of this article is to evaluate whether there is a direct association between the presence of FD and the severity of impaired sleep quality, and to calculate the economic loss due to the decreased work productivity associated with sleep quality.
In Study 1, using a web-based survey completed by workers with and without FD, we evaluated impaired sleep quality, work and daily productivity, and the severity of reflux and bowel symptoms. In Study 2, the association between the presence of FD and the severity of impaired sleep quality was validated in a hospital-based cohort.
In both Study 1 and 2, although impaired sleep quality was more frequent in participants with FD than in those without FD, the independent association between the presence of FD and the severity of impaired sleep quality was not observed after adjustment for the severity of reflux and bowel symptoms. FD participants with impaired sleep quality reported additional economic loss of 53,500 Japanese yen/month.
Although the association between impaired sleep quality and FD was indirect, concomitant impaired sleep quality could worsen economic loss.
睡眠质量受损很常见,并且会降低功能性消化不良(FD)患者的工作效率。
本文的目的是评估FD的存在与睡眠质量受损严重程度之间是否存在直接关联,并计算与睡眠质量相关的工作效率下降所导致的经济损失。
在研究1中,我们通过对患有和未患有FD的工作人员进行基于网络的调查,评估了睡眠质量受损情况、工作及日常效率,以及反流和肠道症状的严重程度。在研究2中,在一个基于医院的队列中验证了FD的存在与睡眠质量受损严重程度之间的关联。
在研究1和研究2中,虽然FD参与者的睡眠质量受损情况比无FD者更常见,但在对反流和肠道症状的严重程度进行调整后,未观察到FD的存在与睡眠质量受损严重程度之间的独立关联。睡眠质量受损的FD参与者报告每月额外经济损失53,500日元。
虽然睡眠质量受损与FD之间的关联是间接的,但伴随的睡眠质量受损可能会加剧经济损失。