Inhibition by human T-lymphotropic virus (HTLV-I) of T-lymphocyte mitogenesis: failure of exogenous T-cell growth factor to restore responsiveness to lectin.
作者信息
Wainberg M A, Spira B, Boushira M, Margolese R G
出版信息
Immunology. 1985 Jan;54(1):1-7.
Abstract
Various retroviruses, including human T-cell lymphotropic virus (HTLV-I) and avian sarcoma virus (ASV), can prevent coincubated human peripheral lymphocytes from responding efficiently to phytohaemagglutinin. Addition of high concentrations of T-cell growth factor (TCGF) activity usually overcomes this inhibition. However, such restoration of responsiveness does not occur in the case of HTLV-coincubated cells.
摘要
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