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评估[具体内容]对哮喘患者生活质量的影响:一项随机对照研究。 (原文中“of”后面缺少具体内容)

Assessment of significance of on quality of life in asthma patients: A randomized controlled study.

作者信息

Agnihotri Shruti, Kant Surya, Mishra Satyendra Kumar, Verma Ajay

机构信息

Department of Pulmonary Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.

Department of Social Work, Institute of Naturopathic and Yogic Sciences, Lucknow University, Lucknow, Uttar Pradesh, India.

出版信息

Ayu. 2017 Jan-Jun;38(1-2):28-32. doi: 10.4103/ayu.AYU_3_16.

Abstract

BACKGROUND

Asthma is a chronic inflammatory respiratory disease characterized by periodic attacks of wheezing, shortness of breath and a tight feeling in the chest. The current study is based on the effect of on quality of life in asthmatics in Northern India.

MATERIALS AND METHODS

A total of 300 participants of mild-to-moderate persistent asthma (FEV >60%) aged between 12 and 60 years were recruited from the Department of Pulmonary Medicine. Their quality of life was assessed with the help of mini asthma quality-of-life questionnaire (AQLQ) at baseline and then after 3 and 6 month from baseline. Forty-five participants were dropped out during the study while 255 participants completed the study successfully.

RESULTS

In "the group," significant improvements were found in all the subdomains of AQLQ at 3 month and at 6 month in comparison to "the control group." The number needed to treat was found to be 2.67 for the total AQLQ score which was greater than the minimal important difference.

CONCLUSION

"The group" got significantly better improvement in asthma quality-of-life scores than "the control group." Thus, can be used as an adjuvant therapy in the management of asthma.

摘要

背景

哮喘是一种慢性炎症性呼吸系统疾病,其特征为喘息、呼吸急促和胸部紧绷感的周期性发作。当前研究基于[未提及的某种因素]对印度北部哮喘患者生活质量的影响。

材料与方法

从肺科招募了300名年龄在12至60岁之间的轻至中度持续性哮喘患者(FEV>60%)。在基线时以及基线后3个月和6个月,借助小型哮喘生活质量问卷(AQLQ)对他们的生活质量进行评估。在研究期间有45名参与者退出,而255名参与者成功完成了研究。

结果

与“对照组”相比,“[未提及的组]”在3个月和6个月时AQLQ的所有子领域均有显著改善。发现总AQLQ评分的治疗所需人数为2.67,大于最小重要差异。

结论

“[未提及的组]”在哮喘生活质量评分方面的改善明显优于“对照组”。因此,[未提及的因素]可作为哮喘管理中的辅助治疗方法。

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