力学微生物学：机械力如何激活金黄色葡萄球菌黏附。
Mechanomicrobiology: How Mechanical Forces Activate Staphylococcus aureus Adhesion.
机构信息
Department of Microbiology, Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
Institute of Life Sciences, Université catholique de Louvain, Croix du Sud, 4-5, bte L7.07.06., B-1348 Louvain-la-Neuve, Belgium; Walloon Excellence in Life Sciences and Biotechnology (WELBIO), Belgium.
出版信息
Trends Microbiol. 2018 Aug;26(8):645-648. doi: 10.1016/j.tim.2018.05.004. Epub 2018 Jun 1.
During colonization of biomaterials and host tissues, surface-attached bacteria are subjected to mechanical stresses, including hydrodynamic flow and cell-surface contacts. Two publications show that mechanical force activates the adhesive function of Staphylococcus aureus surface proteins, thereby providing the pathogen with a means to withstand high shear stress during colonization.
在生物材料和宿主组织的定殖过程中，表面附着的细菌会受到机械应力的作用，包括流体动力学流动和细胞表面接触。有两篇论文表明，机械力会激活金黄色葡萄球菌表面蛋白的黏附功能，从而为病原体提供了一种在定植过程中抵抗高剪切应力的手段。
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