Anthony Nolan Research Institute, London, UK.
UCL Cancer Institute, University College London, London, UK.
Immunogenetics. 2018 Sep;70(9):571-583. doi: 10.1007/s00251-018-1064-4. Epub 2018 Jun 4.
The increasing number of Killer Immunoglobulin-like Receptor (KIR) sequences available for non-human primate species and cattle has prompted development of a centralized database, guidelines for a standardized nomenclature, and minimum requirements for database submission. The guidelines and nomenclature are based on those used for human KIR and incorporate modifications made for inclusion of non-human species in the companion IPD-NHKIR database. Included in this first release are the rhesus macaque (Macaca mulatta), chimpanzee (Pan troglodytes), orangutan (Pongo abelii and Pongo pygmaeus), and cattle (Bos taurus).
越来越多的非人类灵长类动物和牛的杀伤细胞免疫球蛋白样受体 (KIR) 序列可供使用,这促使人们开发了一个集中的数据库,制定了标准化命名法的指南,并为数据库提交制定了最低要求。这些指南和命名法基于人类 KIR 使用的指南,并包含了为在 IPD-NHKIR 数据库中包含非人类物种而进行的修改。在这个首次发布中,包括恒河猴 (Macaca mulatta)、黑猩猩 (Pan troglodytes)、猩猩 (Pongo abelii 和 Pongo pygmaeus) 和牛 (Bos taurus)。