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根除治疗对血脂水平的影响。

Effects of eradication on serum lipid levels.

作者信息

Adachi Kyoichi, Mishiro Tomoko, Toda Takashi, Kano Naomi, Fujihara Harumi, Mishima Yuko, Konishi Atsuko, Mochida Mariko, Takahashi Kazuko, Kinoshita Yoshikazu

机构信息

Health Center, Shimane Environment and Health Public Corporation, Koshibara 1-4-6, Matsue, Shimane 690-0012, Japan.

Clinical Laboratory, Shimane Environment and Health Public Corporation, Matsue, Shimane 690-0012, Japan.

出版信息

J Clin Biochem Nutr. 2018 May;62(3):264-269. doi: 10.3164/jcbn.17-88. Epub 2018 Jan 27.

Abstract

The purpose was to clarify the effects of () eradication on the changes in serum lipid levels by comparing subjects with and without continuous infection. The study subjects were 774 individuals (males 536, females 238, mean age 52.6 years) who visited between April 2013 and March 2016 for annual medical checkups. Serum total cholesterol, high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol (LDLC), and triglyceride levels, and LDLC/HDLC ratio were compared between the subjects with and without infection, as well as those with eradication subjects. The HDLC level in the -positive group was significantly lower as compared to the -negative group. The serum level of HDLC in subjects with successful eradication of tended to be higher, while the serum levels of total cholesterol, LDLC, and triglycerides tended to be lower in comparison to subjects with continuous infection. In addition, the LDLC/HDLC ratio in the -positive group was significantly higher than that in the -negative group, and successful eradication tended to reduce that ratio. In conclusion, successful eradication of may have favorable effects on lipid metabolism.

摘要

目的是通过比较有和没有持续感染的受试者,阐明()根除对血清脂质水平变化的影响。研究对象为2013年4月至2016年3月期间前来进行年度体检的774人(男性536人,女性238人,平均年龄52.6岁)。比较了有和没有感染的受试者以及有根除受试者之间的血清总胆固醇、高密度脂蛋白胆固醇(HDLC)、低密度脂蛋白胆固醇(LDLC)和甘油三酯水平,以及LDLC/HDLC比值。与阴性组相比,阳性组的HDLC水平显著降低。成功根除的受试者的血清HDLC水平趋于升高,而与持续感染的受试者相比,总胆固醇、LDLC和甘油三酯的血清水平趋于降低。此外,阳性组的LDLC/HDLC比值显著高于阴性组,成功根除往往会降低该比值。总之,成功根除可能对脂质代谢有有利影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0c/5990401/faefcd610eef/jcbn17-88f01.jpg

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