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钛制备富血小板纤维蛋白与同种异体移植材料在窦底提升术中的临床、影像学及组织学效果比较

Comparison of the clinical, radiographic, and histological effects of titanium-prepared platelet rich fibrin to allograft materials in sinus-lifting procedures.

作者信息

Olgun Ebru, Ozkan Serdar Y, Atmaca Hasan T, Yalim Mehmet, Hendek Meltem Karsiyaka

机构信息

Department of Periodontology, Faculty of Dentistry, Kirikkale University, Kirikkale, Turkey.

Private Practice, Antalya, Turkey.

出版信息

J Investig Clin Dent. 2018 Nov;9(4):e12347. doi: 10.1111/jicd.12347. Epub 2018 Jun 12.

DOI:10.1111/jicd.12347
PMID:29893477
Abstract

AIM

In the present study, we evaluated the clinical, radiographic, and histological comparisons of completely autologous titanium-prepared platelet rich fibrin (T-PRF) or allograft in sinus-lifting procedures.

METHODS

Eighteen posterior maxilla requiring sinus-lifting procedures using the balloon-lifting technique for implant placement were selected. Ten sinuses were randomly assigned to T-PRF as the test group and eight to allografts as the control group. After 4 and 6 months in the test and control groups, respectively, computed tomography was done, and bone samples were received during implant surgery. Three months after the second surgery, implant stability was measured.

RESULTS

Radiological results showed that the allograft group had better results (62% in volume, 53% in density, and 69% in height) than the T-PRF group. Histomorphometric results showed that newly-formed bone ratios were 17.28 ± 2.53 and 16.58 ± 1.05 in the allograft group and T-PRF groups, respectively. There was no significant difference between the test and control groups (P = .611) for implant stability values.

CONCLUSIONS

The use of T-PRF alone in sinus-lifting operations has successful clinical and histomorphometric results. Bone formation in the T-PRF group was accelerated to 4 months compared to allografts according to the histological results.

摘要

目的

在本研究中,我们评估了在鼻窦提升手术中完全自体钛制备富血小板纤维蛋白(T-PRF)或同种异体移植物的临床、影像学和组织学比较。

方法

选择18例需要使用球囊提升技术进行上颌窦提升手术以植入种植体的后牙区上颌骨。10个鼻窦随机分配至T-PRF组作为试验组,8个鼻窦分配至同种异体移植物组作为对照组。试验组和对照组分别在4个月和6个月后进行计算机断层扫描,并在种植手术期间获取骨样本。第二次手术后3个月,测量种植体稳定性。

结果

影像学结果显示,同种异体移植物组(体积62%、密度53%、高度69%)比T-PRF组有更好的结果。组织形态计量学结果显示,同种异体移植物组和T-PRF组的新形成骨比例分别为17.28±2.53和16.58±1.05。试验组和对照组的种植体稳定性值无显著差异(P = 0.611)。

结论

在鼻窦提升手术中单独使用T-PRF具有成功的临床和组织形态计量学结果。根据组织学结果,与同种异体移植物相比,T-PRF组的骨形成加速至4个月。

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