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自然接触过中东呼吸综合征冠状病毒的以色列美洲驼、羊驼和骆驼体内的特异性抗体

Middle East respiratory syndrome coronavirus specific antibodies in naturally exposed Israeli llamas, alpacas and camels.

作者信息

David Dan, Rotenberg Ditza, Khinich Evgeny, Erster Oran, Bardenstein Svetlana, van Straten Michael, Okba Nisreen M A, Raj Stalin V, Haagmans Bart L, Miculitzki Marcelo, Davidson Irit

机构信息

Kimron Veterinary Institute, Bet Dagan, Israel.

Hachaklait, Veterinary Services, Caesarea, Israel.

出版信息

One Health. 2018 May 4;5:65-68. doi: 10.1016/j.onehlt.2018.05.002. eCollection 2018 Jun.

DOI:10.1016/j.onehlt.2018.05.002
PMID:29911167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6000904/
Abstract

Thus far, no human MERS-CoV infections have been reported from Israel. Evidence for the circulation of MERS-CoV in dromedaries has been reported from almost all the countries of the Middle East, except Israel. Therefore, we aimed to analyze MERS-CoV infection in Israeli camelids, sampled between 2012 and 2017. A total of 411 camels, 102 alpacas and 19 llamas' sera were tested for the presence of antibodies to MERS-CoV. Our findings indicate a lower MERS-CoV seropositivity among Israeli dromedaries than in the surrounding countries, and for the first time naturally infected llamas were identified. In addition, nasal swabs of 661 camels, alpacas and lamas, obtained from January 2015 to December 2017, were tested for the presence of MERS-CoV RNA. All nasal swabs were negative, indicating no evidence for MERS-CoV active circulation in these camelids during that time period.

摘要

迄今为止,以色列尚未报告有人感染中东呼吸综合征冠状病毒(MERS-CoV)。除以色列外,中东几乎所有国家均报告了单峰骆驼中存在MERS-CoV传播的证据。因此,我们旨在分析2012年至2017年间采样的以色列骆驼科动物中的MERS-CoV感染情况。共检测了411头骆驼、102只羊驼和19只美洲驼的血清中是否存在抗MERS-CoV抗体。我们的研究结果表明,以色列单峰骆驼的MERS-CoV血清阳性率低于周边国家,并且首次鉴定出自然感染的美洲驼。此外,对2015年1月至2017年12月采集的661头骆驼、羊驼和美洲驼的鼻拭子进行了检测,以确定是否存在MERS-CoV RNA。所有鼻拭子均为阴性,表明在此期间这些骆驼科动物中没有MERS-CoV活跃传播的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdaa/6000904/0bcfe12f8fb7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdaa/6000904/9a9ec302a393/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdaa/6000904/e24f44777a52/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdaa/6000904/0bcfe12f8fb7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdaa/6000904/9a9ec302a393/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdaa/6000904/e24f44777a52/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdaa/6000904/0bcfe12f8fb7/gr3.jpg

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