Center for Breast Cancer, Hospital, National Cancer Center, Goyang, South Korea.
Center for Clinical Epidemiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Eur J Hum Genet. 2018 Oct;26(10):1432-1440. doi: 10.1038/s41431-018-0191-6. Epub 2018 Jun 18.
With further advances in medical genetics, genetic tests to determine predisposition to disease are becoming viable for a growing number of diseases. Accordingly, it has also become important to identify various viewpoints on genetic testing. The aims of this study were to examine awareness of and attitudes toward genetic testing among the general public (public), cancer patients (patients), and health-care professionals (clinicians and researchers) in Korea. The present survey was conducted from November 2016 to February 2017. The public and patients were surveyed via face-to-face interviews conducted by trained interviewers. Health-care professionals were surveyed via self-administered questionnaires. In total, 1500 individuals from the general public, 1500 cancer patients, 113 clinicians, and 413 researchers were surveyed. Most respondents from the public and patients had previously heard about genetic testing (public, 89.4%; patients, 92.7%, p < 0.01). Differences in attitudes toward genetic testing among the public, patients, and professionals were noted, although most respondents in the present study were aware of genetic testing. Most of the cancer patients tended to overestimate the potential benefit of genetic testing, whereas clinicians expressed concerns for genetic testing. Providing correct information to people who are scheduled to undergo or order genetic testing could help in making an informed decision thereon.
随着医学遗传学的进一步发展，越来越多的疾病可以进行确定疾病易感性的基因检测。因此，确定对基因检测的各种观点也变得很重要。本研究的目的是检验韩国普通公众（公众）、癌症患者（患者）和医疗保健专业人员（临床医生和研究人员）对基因检测的认识和态度。本调查于 2016 年 11 月至 2017 年 2 月进行。通过经过培训的访谈员进行面对面访谈对公众和患者进行调查。通过自我管理问卷对医疗保健专业人员进行调查。共调查了来自普通公众的 1500 人、癌症患者的 1500 人、临床医生的 113 人和研究人员的 413 人。大多数公众和患者之前都听说过基因检测（公众，89.4%；患者，92.7%，p<0.01）。尽管本研究中的大多数受访者都了解基因检测，但公众、患者和专业人员对基因检测的态度存在差异。大多数癌症患者往往高估了基因检测的潜在益处，而临床医生则对基因检测表示担忧。向计划进行或订购基因检测的人提供正确的信息可以帮助他们在这方面做出明智的决定。
