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东南亚的抗菌素耐药性:是时候提出正确的问题了。

Antimicrobial resistance in South East Asia: time to ask the right questions.

作者信息

Kakkar Manish, Chatterjee Pranab, Chauhan Abhimanyu Singh, Grace Delia, Lindahl Johanna, Beeche Arlyne, Jing Fang, Chotinan Suwit

机构信息

a Public Health Foundation of India , Gurgaon , Haryana , India.

b Indian Council of Medical Research , National Institute of Cholera and Enteric Diseases , Kolkata , West Bengal , India.

出版信息

Glob Health Action. 2018;11(1):1483637. doi: 10.1080/16549716.2018.1483637.

Abstract

Antimicrobial resistance (AMR) has emerged as a major public health concern, around which the international leadership has come together to form strategic partnerships and action plans. The main driving force behind the emergence of AMR is selection pressure created due to consumption of antibiotics. Consumption of antibiotics in human as well as animal sectors are driven by a complex interplay of determinants, many of which are typical to the local settings. Several sensitive and essential realities are tied with antibiotic consumption - food security, livelihoods, poverty alleviation, healthcare access and national economies, to name a few. That makes one-size-fits-all policies, framed with the developed country context in mind, inappropriate for developing countries. Many countries in the South East Asian Region have some policy structures in place to deal with AMR, but most of them lack detailed implementation plans or monitoring structures. In this current debates piece, the authors argue that the principles driving the AMR agenda in the South East Asian countries need to be dealt with using locally relevant policy structures. Strategies, which have successfully reduced the burden of AMR in the developed countries, should be evaluated in the developing country contexts instead of ad hoc implementation. The Global Action Plan on AMR encourages member states to develop locally relevant National Action Plans on AMR. This policy position should be leveraged to develop and deploy locally relevant strategies, which are based on a situation analysis of the local systems, and are likely to meet the needs of the individual member states.

摘要

抗菌药物耐药性(AMR)已成为一个主要的公共卫生问题,国际社会的领导层围绕这一问题共同组建了战略伙伴关系并制定了行动计划。AMR出现的主要驱动力是抗生素使用所产生的选择压力。人类和动物领域抗生素的使用受到多种决定因素复杂相互作用的驱动,其中许多因素是当地特有的。抗生素使用与一些敏感且至关重要的现实情况相关联——粮食安全、生计、减贫、医疗保健可及性和国家经济等等。这使得那些基于发达国家背景制定的一刀切政策不适用于发展中国家。东南亚区域的许多国家已制定了一些应对AMR的政策框架,但其中大多数缺乏详细的实施计划或监测架构。在这篇当前的辩论文章中,作者认为,需要利用与当地相关的政策框架来处理推动东南亚国家AMR议程的各项原则。在发展中国家背景下,应评估那些在发达国家成功减轻了AMR负担的策略,而不是临时实施。《全球抗菌药物耐药性行动计划》鼓励成员国制定与当地相关的国家抗菌药物耐药性行动计划。应利用这一政策立场来制定和部署基于当地系统情况分析且可能满足各成员国需求的与当地相关的策略。

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