Reassessment of c-Kit in Cardiac Cells: A Complex Interplay Between Expression, Fate, and Function.
作者信息
Zhou Bin, Wu Sean M
机构信息
From the State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China (B.Z.)
Division of Cardiovascular Medicine, Department of Medicine, Cardiovascular Institute, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, CA (S.M.W.).
出版信息
Circ Res. 2018 Jun 22;123(1):9-11. doi: 10.1161/CIRCRESAHA.118.313215.
Abstract
摘要
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本文引用的文献
1
Cardiac c-Kit Biology Revealed by Inducible Transgenesis.诱导性转基因揭示心脏 c-Kit 生物学
Circ Res. 2018 Jun 22;123(1):57-72. doi: 10.1161/CIRCRESAHA.117.311828. Epub 2018 Apr 10.
2
Kit knock-in mice fail to fate-map cardiac stem cells.试剂盒敲入小鼠无法对心脏干细胞进行命运图谱分析。
Nature. 2018 Mar 21;555(7697):E1-E5. doi: 10.1038/nature25771.
3
Enhancing the precision of genetic lineage tracing using dual recombinases.使用双重组酶提高遗传谱系追踪的精度。
Nat Med. 2017 Dec;23(12):1488-1498. doi: 10.1038/nm.4437. Epub 2017 Nov 13.
4
Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes.遗传谱系追踪鉴定出原位表达Kit的心肌细胞。
Cell Res. 2016 Jan;26(1):119-30. doi: 10.1038/cr.2015.143. Epub 2015 Dec 4.
5
Resident c-kit(+) cells in the heart are not cardiac stem cells.心脏中的常驻c-kit(+)细胞并非心脏干细胞。
Nat Commun. 2015 Oct 30;6:8701. doi: 10.1038/ncomms9701.
6
cKit+ cardiac progenitors of neural crest origin.神经嵴来源的cKit+心脏祖细胞。
Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13051-6. doi: 10.1073/pnas.1517201112. Epub 2015 Oct 5.
7
c-kit+ cells minimally contribute cardiomyocytes to the heart.c-kit+ 细胞对心脏的心肌细胞生成贡献极小。
Nature. 2014 May 15;509(7500):337-41. doi: 10.1038/nature13309. Epub 2014 May 7.
8
Concise review: The role of C-kit expressing cells in heart repair at the neonatal and adult stage.简要综述：C-kit表达细胞在新生儿和成年期心脏修复中的作用。
Stem Cells. 2014 Jul;32(7):1701-12. doi: 10.1002/stem.1696.
9
Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy.经心内膜与冠状动脉内移植 CD34+ 细胞治疗非缺血性扩张型心肌病的比较。
Circulation. 2013 Sep 10;128(11 Suppl 1):S42-9. doi: 10.1161/CIRCULATIONAHA.112.000230.
10
Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair.成体 c-kit（阳性）心脏干细胞对于功能性心脏再生和修复是必需且充分的。
Cell. 2013 Aug 15;154(4):827-42. doi: 10.1016/j.cell.2013.07.039.
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