Singer A, Wilters J, Walker P, Jenkins D, Slavin G, Cowdell H, To A, Husain O
J Clin Pathol. 1985 Aug;38(8):855-7. doi: 10.1136/jcp.38.8.855.
Human papillomavirus antigen was found in 39 (16%) of 253 colposcopic biopsies from a group of women at high risk for cervical cancer who had been examined in the early 1970s. Immunohistochemical evidence of papillomavirus infection was found in 20 (30%) of 67 cervical intraepithelial neoplasia lesions infected with wart virus from these patients. When these results were compared with results of a similar study carried out in the early 1980s there was no significant difference in the prevalence of human papillomavirus antigen in cervical intraepithelial neoplasia lesions infected with wart virus from women who had been examined over a decade apart.
在20世纪70年代早期接受检查的一组宫颈癌高危女性的253份阴道镜活检样本中,发现39份(16%)含有人类乳头瘤病毒抗原。在这些患者感染疣病毒的67例宫颈上皮内瘤变病变中,20例(30%)发现了乳头瘤病毒感染的免疫组化证据。将这些结果与20世纪80年代早期进行的一项类似研究的结果相比较,在相隔十多年接受检查的女性感染疣病毒的宫颈上皮内瘤变病变中,人类乳头瘤病毒抗原的患病率没有显著差异。