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来自大肠杆菌K-12的DeoR阻遏物的一级结构。

The primary structure of the DeoR repressor from Escherichia coli K-12.

作者信息

Valentin-Hansen P, Højrup P, Short S

出版信息

Nucleic Acids Res. 1985 Aug 26;13(16):5927-36. doi: 10.1093/nar/13.16.5927.

DOI:10.1093/nar/13.16.5927
PMID:2994018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC321923/
Abstract

The nucleotide sequence of the deoR gene of E. coli, which codes for the DeoR repressor, has been determined. This gene codes for a polypeptide that is 252 amino acids residues in length. Computer-assisted analysis of the nucleotide sequence strongly suggests that the DNA binding domain of the DeoR repressor is located in the N-terminal part of the protein. After the coding region there is a dyad symmetry similar to a palindromic unit present outside many structural genes on the E. coli chromosome.

摘要

已确定大肠杆菌中编码DeoR阻遏物的deoR基因的核苷酸序列。该基因编码一个长度为252个氨基酸残基的多肽。对核苷酸序列的计算机辅助分析强烈表明,DeoR阻遏物的DNA结合结构域位于该蛋白质的N端部分。在编码区之后有一个二元对称结构,类似于大肠杆菌染色体上许多结构基因外存在的回文单元。

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本文引用的文献

1
The structure of tandem regulatory regions in the deo operon of Escherichia coli K12.大肠杆菌 K12 的 deo 操纵子中串联调节区的结构。
EMBO J. 1982;1(3):317-22. doi: 10.1002/j.1460-2075.1982.tb01167.x.
2
The operator-binding domain of lambda repressor: structure and DNA recognition.λ阻遏蛋白的操纵子结合结构域:结构与DNA识别
Nature. 1982 Jul 29;298(5873):443-7. doi: 10.1038/298443a0.
3
Functions related to the receptor protein specified by the tsx gene of Escherichia coli.与大肠杆菌tsx基因所指定的受体蛋白相关的功能。
Arch Microbiol. 1980 Feb;124(2-3):233-42. doi: 10.1007/BF00427732.
4
Codon catalog usage and the genome hypothesis.密码子目录使用与基因组假说。
Nucleic Acids Res. 1980 Jan 11;8(1):r49-r62. doi: 10.1093/nar/8.1.197-c.
5
Homology among DNA-binding proteins suggests use of a conserved super-secondary structure.DNA结合蛋白之间的同源性表明存在保守的超二级结构。
Nature. 1982 Jul 29;298(5873):447-51. doi: 10.1038/298447a0.
6
Structure of the cro repressor from bacteriophage lambda and its interaction with DNA.来自噬菌体λ的cro阻遏蛋白的结构及其与DNA的相互作用。
Nature. 1981 Apr 30;290(5809):754-8. doi: 10.1038/290754a0.
7
Demonstration of two operator elements in gal: in vitro repressor binding studies.gal中两个操纵基因元件的证明:体外阻遏物结合研究
Proc Natl Acad Sci U S A. 1984 Oct;81(19):6100-4. doi: 10.1073/pnas.81.19.6100.
8
A family of dispersed repetitive extragenic palindromic DNA sequences in E. coli.大肠杆菌中一类分散的重复基因外回文DNA序列家族。
EMBO J. 1984 Jun;3(6):1417-21. doi: 10.1002/j.1460-2075.1984.tb01986.x.
9
Repetitive extragenic palindromic sequences: a major component of the bacterial genome.重复基因外回文序列:细菌基因组的主要组成部分。
Cell. 1984 Jul;37(3):1015-26. doi: 10.1016/0092-8674(84)90436-7.
10
Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity.由静电互补性提出的分解代谢物基因激活蛋白与B-DNA之间特定复合物的模型。
Proc Natl Acad Sci U S A. 1984 Jul;81(13):3973-7. doi: 10.1073/pnas.81.13.3973.