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诊断中的纳米生物传感器

Nanobiosensors in diagnostics.

作者信息

Chamorro-Garcia Alejandro, Merkoçi Arben

机构信息

Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technolgy, Campus UAB, Bellaterra, 08193 Barcelona, Spain.

ICREA, Pg. Lluís Companys 23, 08010 Barcelona, Spain.

出版信息

Nanobiomedicine (Rij). 2016 Nov 24;3:1849543516663574. doi: 10.1177/1849543516663574. eCollection 2016 Jan-Dec.

Abstract

Medical diagnosis has been greatly improved thanks to the development of new techniques capable of performing very sensitive detection and quantifying certain parameters. These parameters can be correlated with the presence of specific molecules and their quantity. Unfortunately, these techniques are demanding, expensive, and often complicated. On the other side, progress in other fields of science and technology has contributed to the rapid growth of nanotechnology. Although being an emerging discipline, nanotechnology has raised huge interest and expectations. Most of the enthusiasm comes from new possibilities and properties of nanomaterials. Biosensors (simple, robust, sensitive, cost-effective) combined with nanomaterials, also called nanobiosensors, are serving as bridge between advanced detection/diagnostics and daily/routine tests. Here we review some of the latest applications of nanobiosensors in diagnostics field.

摘要

由于能够进行非常灵敏的检测和定量某些参数的新技术的发展,医学诊断有了很大的改善。这些参数可以与特定分子的存在及其数量相关联。不幸的是,这些技术要求苛刻、成本高昂且往往很复杂。另一方面,其他科学技术领域的进展推动了纳米技术的迅速发展。尽管纳米技术是一门新兴学科,但它已经引起了极大的兴趣和期望。大部分热情来自于纳米材料的新可能性和特性。与纳米材料相结合的生物传感器(简单、坚固、灵敏、经济高效),也称为纳米生物传感器,正充当着先进检测/诊断与日常/常规测试之间的桥梁。在此,我们回顾纳米生物传感器在诊断领域的一些最新应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fb4/5998262/66518a23e89e/10.1177_1849543516663574-fig1.jpg

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