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天麻炮制加工、成分分析及体内代谢的研究进展

[Research progress of Gastrodiae Rhizoma machining processing, composition analysis and in vivo metabolism].

作者信息

Yang Fei, Wang Xin, Ma Chuan-Jiang, Chen Ya-Hui, Sun Ai-Ping, Jia Jing, Cao Guang-Shang, Xin Yi-Zhou, Zhang Xue-Shun

机构信息

Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.

Shandong Institute of Prescription-based Processing of Traditional Chinese Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji'nan 250011, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2018 Jun;43(11):2207-2215. doi: 10.19540/j.cnki.cjcmm.20180322.008.

Abstract

Steaming method is a traditional processing method for Gastrodiae Rhizoma(GR). The current studies on the steaming method's mechanism of GR are mainly focused on facilitating softening slice, destroying the β-glycosidic bond enzymes to reduce the decomposition of gastrodia glycosides (killing enzyme and protecting glycosides). The researches on the processing mechanism are still incomplete, while revealing and analyzing the active components in the body's metabolic process are important channels and new models to clarify the mechanism of traditional medicine processing. In order to provides a reference for the in-depth study of the processing mechanism of GR, we have reviewed the relevant literature at home and abroad in recent years and briefly summarized the processing, composition analysis and in vivo metabolism of GR in this study.

摘要

蒸制方法是天麻的传统炮制方法。目前关于天麻蒸制方法的机制研究主要集中在便于软化切片、破坏β-糖苷键酶以减少天麻苷的分解(杀酶保苷)。对炮制机制的研究仍不完整,而揭示和分析体内代谢过程中的活性成分是阐明中药炮制机制的重要途径和新模型。为了为深入研究天麻的炮制机制提供参考,我们查阅了近年来国内外的相关文献,并在本研究中简要总结了天麻的炮制、成分分析及体内代谢情况。

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