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组建多机构跨学科团队以制定人畜共患结核病路线图。

Building a Multi-Institutional and Interdisciplinary Team to Develop a Zoonotic Tuberculosis Roadmap.

作者信息

Olea-Popelka Francisco, Fujiwara Paula I

机构信息

Mycobacteria Research Laboratories, Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.

International Union Against Tuberculosis and Lung Disease, Paris, France.

出版信息

Front Public Health. 2018 Jun 12;6:167. doi: 10.3389/fpubh.2018.00167. eCollection 2018.

Abstract

Tuberculosis (TB), as the major infectious disease in the world, has devastating consequences for not only humans, but also cattle and several wildlife species. This disease presents additional challenges to human and veterinary health authorities given the zoonotic nature of the pathogens responsible for the disease across species. One of the main public health challenges regarding zoonotic TB (ZTB) caused by Mycobacterium bovis is that the true incidence of this type of TB in humans is not known and is likely to be underestimated. To effectively address challenges posed by ZTB, an integrated One Health approach is needed. In this manuscript, we describe the rationale, major steps, timeline, stakeholders, and important events that led to the assembling of a true integrated multi-institutional and interdisciplinary team that accomplished the ambitious goal of developing a ZTB roadmap, published in October, 2017. It outlines key activities to address the global challenges regarding the prevention, surveillance, diagnosis, and treatment of ZTB. We discuss and emphasize the importance of integrated approaches to be able to accomplish the short (year 2020) and medium term (year 2025) goals outlined in the ZTB roadmap.

摘要

结核病作为全球主要的传染病,不仅对人类,而且对牛和几种野生动物都具有毁灭性后果。鉴于导致该疾病的病原体具有跨物种的人畜共患病性质,这种疾病给人类和兽医卫生当局带来了额外的挑战。由牛分枝杆菌引起的人畜共患结核病(ZTB)面临的主要公共卫生挑战之一是,这种类型的结核病在人类中的真实发病率尚不清楚,而且很可能被低估。为了有效应对ZTB带来的挑战,需要采取综合的“同一健康”方法。在本手稿中,我们描述了促成组建一个真正的综合多机构和跨学科团队的基本原理、主要步骤、时间表、利益相关者以及重要事件,该团队实现了制定ZTB路线图这一宏伟目标,并于2017年10月发布。它概述了应对ZTB预防、监测、诊断和治疗方面全球挑战的关键活动。我们讨论并强调综合方法对于实现ZTB路线图中概述的短期(2020年)和中期(2025年)目标的重要性。

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