Organelle Biology and Cellular Ageing Lab, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India.
Viral Immunology Lab, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India.
Microbes Infect. 2019 Jan-Feb;21(1):20-32. doi: 10.1016/j.micinf.2018.06.002. Epub 2018 Jun 25.
Viruses are obligate intracellular parasites of the host cells. A commonly accepted view is the requirement of internal membranous structures for various aspects of viral life cycle. Organelles enable favourable intracellular environment for several viruses. However, studies reporting organelle dynamics upon viral infections are scant. In this review, we aim to summarize and highlight modulations caused to various organelles upon viral infection or expression of its proteins.
病毒是宿主细胞的专性细胞内寄生虫。人们普遍认为，病毒生命周期的各个方面都需要内部膜结构。细胞器使多种病毒能够在有利的细胞内环境中生存。然而，目前关于病毒感染时细胞器动态变化的研究还很少。在这篇综述中，我们旨在总结和强调病毒感染或其蛋白表达时对各种细胞器造成的影响。
