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Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.利用癌症信号传导及其他疾病中的Ref-1-APE1节点：从实验室到临床
NPJ Precis Oncol. 2017;1. doi: 10.1038/s41698-017-0023-0. Epub 2017 Jun 8.
2
Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer.使用一种新型的NQO1生物可激活药物β-拉帕醌（ARQ761），通过代谢调节增强胰腺癌的化疗效果。
J Surg Oncol. 2017 Jul;116(1):83-88. doi: 10.1002/jso.24624. Epub 2017 Mar 27.
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NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.NRF2通过调节胰腺癌中的mRNA翻译促进肿瘤维持。
Cell. 2016 Aug 11;166(4):963-976. doi: 10.1016/j.cell.2016.06.056. Epub 2016 Jul 28.
4
Association between intake of antioxidants and pancreatic cancer risk: a meta-analysis.抗氧化剂摄入量与胰腺癌风险之间的关联：一项荟萃分析。
Int J Food Sci Nutr. 2016 Nov;67(7):744-53. doi: 10.1080/09637486.2016.1197892. Epub 2016 Jun 30.
5
Annual Report to the Nation on the Status of Cancer, 1975-2012, featuring the increasing incidence of liver cancer.《1975 - 2012年美国癌症现状年度报告》，重点关注肝癌发病率上升情况
Cancer. 2016 May 1;122(9):1312-37. doi: 10.1002/cncr.29936. Epub 2016 Mar 9.
6
A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia.一项维生素 E δ-生育三烯酚用于胰腺导管内肿瘤患者的 I 期安全性、药代动力学和药效学的术前研究。
EBioMedicine. 2015 Nov 14;2(12):1987-95. doi: 10.1016/j.ebiom.2015.11.025. eCollection 2015 Dec.
7
Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer.药理学剂量的维生素C可使胰腺癌对放疗敏感。
Cancer Res. 2015 Aug 15;75(16):3314-26. doi: 10.1158/0008-5472.CAN-14-1707. Epub 2015 Jun 16.
8
Vitamin E δ-tocotrienol prolongs survival in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) transgenic mouse model of pancreatic cancer.维生素 E δ-生育三烯酚延长 LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) 转基因胰腺癌小鼠模型的存活时间。
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Treating pancreatic cancer: more antioxidants more problems?

作者信息

Alexander Matthew S, Cullen Joseph J

机构信息

a Departments of Surgery and Radiation Oncology, Holden Comprehensive Cancer Center , The University of Iowa Hospitals and Clinics and the University of Iowa College of Medicine , Iowa City , IA , USA.

出版信息

Expert Rev Gastroenterol Hepatol. 2018 Sep;12(9):849-851. doi: 10.1080/17474124.2018.1494572. Epub 2018 Jul 5.

DOI:10.1080/17474124.2018.1494572
PMID:29956580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6317716/
Abstract
摘要