Suppr超能文献

使用修订后的世界卫生组织聚类抽样调查方法分类肯尼亚 47 个县 2016 年麻疹-风疹疫苗接种运动的覆盖情况。

Use of the revised World Health Organization cluster survey methodology to classify measles-rubella vaccination campaign coverage in 47 counties in Kenya, 2016.

机构信息

Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.

Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.

出版信息

PLoS One. 2018 Jul 2;13(7):e0199786. doi: 10.1371/journal.pone.0199786. eCollection 2018.

Abstract

INTRODUCTION

To achieve measles elimination, two doses of measles-containing vaccine (MCV) are provided through routine immunization services or vaccination campaigns. In May 2016, Kenya conducted a measles-rubella (MR) vaccination campaign targeting 19 million children aged 9 months-14 years, with a goal of achieving ≥95% coverage. We conducted a post-campaign cluster survey to estimate national coverage and classify coverage in Kenya's 47 counties.

METHODS

The stratified multi-stage cluster survey included data from 20,011 children in 8,253 households sampled using the recently revised World Health Organization coverage survey methodology (2015). Point estimates and 95% confidence intervals (95% CI) of national campaign coverage were calculated, accounting for study design. County vaccination coverage was classified as 'pass,' 'fail,' or 'intermediate,' using one-sided hypothesis tests against a 95% threshold.

RESULTS

Estimated national MR campaign coverage was 95% (95% CI: 94%-96%). Coverage differed significantly (p < 0.05) by child's school attendance, mother's education, household wealth, and other factors. In classifying coverage, 20 counties passed (≥95%), two failed (<95%), and 25 were intermediate (unable to classify either way). Reported campaign awareness among caretakers was 92%. After the 2016 MR campaign, an estimated 93% (95% CI: 92%-94%) of children aged 9 months to 14 years had received ≥2 MCV doses; 6% (95% CI: 6%-7%) had 1 MCV dose; and 0.7% (95% CI: 0.6%-0.9%) remained unvaccinated.

CONCLUSIONS

Kenya reached the MR campaign target of 95% vaccination coverage, representing a substantial achievement towards increasing population immunity. High campaign awareness reflected the comprehensive social mobilization strategy implemented in Kenya and supports the importance of including strong communications platforms in future vaccination campaigns. In counties with sub-optimal MR campaign coverage, further efforts are needed to increase MCV coverage to achieve the national goal of measles elimination by 2020.

摘要

简介

为实现麻疹消除目标,通过常规免疫服务或疫苗接种运动为儿童提供两剂含麻疹成分疫苗(MCV)。2016 年 5 月,肯尼亚针对 1900 万名 9 个月至 14 岁儿童开展了麻疹-风疹(MR)疫苗接种运动,目标是实现覆盖率≥95%。我们开展了一项接种后疫情监测的整群抽样调查,以评估全国的覆盖情况,并对肯尼亚 47 个县的覆盖情况进行分类。

方法

分层多阶段整群抽样调查包括了使用最近修订的世界卫生组织覆盖情况调查方法(2015 年)抽取的 8253 户家庭中的 20011 名儿童的数据。根据研究设计,计算了全国运动覆盖率的点估计值和 95%置信区间(95%CI)。采用单侧假设检验,将 95%的阈值作为对照,将县接种覆盖率分为“合格”、“不合格”或“中间”。

结果

MR 运动全国估计覆盖率为 95%(95%CI:94%-96%)。儿童是否上学、母亲的教育程度、家庭财富和其他因素都对覆盖率有显著影响(p<0.05)。在进行覆盖率分类时,有 20 个县合格(≥95%),2 个县不合格(<95%),25 个县为中间(无法判定)。看护人报告的运动知晓率为 92%。在 2016 年 MR 运动之后,估计有 93%(95%CI:92%-94%)的 9 个月至 14 岁儿童已接种≥2 剂 MCV;6%(95%CI:6%-7%)接种了 1 剂;0.7%(95%CI:0.6%-0.9%)仍未接种。

结论

肯尼亚达到了麻疹风疹运动 95%的接种覆盖率目标,这是朝着提高人群免疫力迈出的重要一步。高覆盖率反映了肯尼亚实施的全面社会动员战略,支持在未来的疫苗接种运动中纳入强大的传播平台。在麻疹风疹运动覆盖率欠佳的县,需要进一步努力提高 MCV 覆盖率,以实现到 2020 年消除麻疹的国家目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfdc/6028100/dd215372746b/pone.0199786.g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验