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代谢健康的肥胖黎巴嫩人高密度脂蛋白胆固醇水平与维生素A摄入量之间的关联:黎巴嫩成年人的一项横断面研究

Association between HDL Cholesterol Levels and the Consumption of Vitamin A in Metabolically Healthy Obese Lebanese: A Cross-Sectional Study among Adults in Lebanon.

作者信息

Zalaket J, Hanna-Wakim L, Matta J

机构信息

Department of Nutrition, Faculty of Agriculture and Food Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon.

出版信息

Cholesterol. 2018 Jun 3;2018:8050512. doi: 10.1155/2018/8050512. eCollection 2018.

Abstract

OBJECTIVES

Previous studies show the association between vitamin A and elevation of plasma triglyceride concentrations. However, limited information exists on the association between vitamin A and plasma HDL cholesterol concentrations. The aim of this study is to investigate the association between plasma HDL cholesterol levels and vitamin A intake in 57 metabolically healthy obese (MHO) Lebanese.

METHODS

Out of the 112 adult obese participants who had completed anthropometric and biochemical data, 57 (22 males and 35 females) aged 18-62 years old are metabolically healthy and their data are included in this study. A valid semiquantitative food frequency questionnaire (SQFFQ) was used to test vitamin A intake among other antioxidants. The participants were recruited from the database of three dietary clinics across Lebanon.

RESULTS

Pearson's correlation coefficient was used to measure the strength of the relationship between vitamin A and plasma HDL cholesterol levels. There was a significant positive correlation ( value = 0.0225) between vitamin A consumption and HDL cholesterol serum levels in obese participants; when vitamin A levels decrease, HDL levels decrease more in female than in male participants.

CONCLUSION

The association between dietary vitamin A, a powerful antioxidant, and high HDL levels is shown in MHO but should be further exploited in future studies.

摘要

目的

先前的研究表明维生素A与血浆甘油三酯浓度升高之间存在关联。然而,关于维生素A与血浆高密度脂蛋白胆固醇(HDL)浓度之间的关联,现有信息有限。本研究的目的是调查57名代谢健康的黎巴嫩肥胖者血浆HDL胆固醇水平与维生素A摄入量之间的关联。

方法

在112名完成人体测量和生化数据的成年肥胖参与者中,57名(22名男性和35名女性)年龄在18 - 62岁之间,代谢健康,他们的数据被纳入本研究。使用有效的半定量食物频率问卷(SQFFQ)来检测维生素A及其他抗氧化剂的摄入量。参与者从黎巴嫩各地三家饮食诊所的数据库中招募。

结果

采用Pearson相关系数来衡量维生素A与血浆HDL胆固醇水平之间关系的强度。肥胖参与者中,维生素A摄入量与HDL胆固醇血清水平之间存在显著正相关(值 = 0.0225);当维生素A水平降低时,女性参与者的HDL水平下降幅度比男性参与者更大。

结论

在代谢健康的肥胖者中显示出强大抗氧化剂膳食维生素A与高HDL水平之间的关联,但在未来研究中应进一步探究。

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