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青少年哮喘及过敏相关疾病的患病率与风险因素(PERFORMANCE)研究:原理与方法

Prevalence and Risk Factors of Asthma and Allergy-Related Diseases among Adolescents (PERFORMANCE) study: rationale and methods.

作者信息

Bhattacharjee Soumya, Haldar Prasun, Gopal Maity Santi, Debnath Smriti, Moitra Saibal, Saha Sujoy, Mitra Ritabrata, Annesi-Maesano Isabella, Garcia-Aymerich Judith, Moitra Subhabrata

机构信息

Dept of Chest Medicine, Murshidabad Medical College and Hospital, Berhampore, India.

These authors contributed equally.

出版信息

ERJ Open Res. 2018 Jun 27;4(2). doi: 10.1183/23120541.00034-2018. eCollection 2018 Apr.

Abstract

Despite a considerable number of international reports on allergic diseases among children, information about the prevalence and risk factors of asthma and allergy-related diseases among Indian adolescents is relatively sparse. The Prevalence and Risk Factors of Asthma and Allergy-Related Diseases among Adolescents (PERFORMANCE) study has been conceived to study the aetiology of asthma and allergic diseases including rhinoconjunctivitis, atopic eczema and food allergies among adolescents in West Bengal, India, using standardised methods and collaborations. The aims of the study are: 1) to estimate the prevalence and risk factors of asthma and allergic diseases among the adolescents residing in rural, suburban and urban areas of West Bengal; 2) to obtain information about the possible role of lifestyle factors (smoking, diet and physical activity) on the disease prevalence; and 3) to create a network for further investigation on social, environmental and genetic factors affecting the diseases. The PERFORMANCE study comprises two phases. The phase I study will investigate the prevalence and possible contributing factors of asthma and allergic diseases in a defined population. The phase II study will be performed as a follow-up of phase I to assess the incidence of asthma and allergic diseases.

摘要

尽管已有大量关于儿童过敏性疾病的国际报告,但关于印度青少年哮喘及过敏相关疾病的患病率和风险因素的信息相对较少。青少年哮喘及过敏相关疾病的患病率和风险因素(PERFORMANCE)研究旨在利用标准化方法和合作,研究印度西孟加拉邦青少年哮喘及包括鼻结膜炎、特应性皮炎和食物过敏在内的过敏性疾病的病因。该研究的目的如下:1)估计居住在西孟加拉邦农村、郊区和城市地区的青少年中哮喘及过敏性疾病的患病率和风险因素;2)获取生活方式因素(吸烟、饮食和体育活动)对疾病患病率可能产生的作用的信息;3)建立一个网络,以便进一步研究影响这些疾病的社会、环境和遗传因素。PERFORMANCE研究包括两个阶段。第一阶段研究将调查特定人群中哮喘及过敏性疾病的患病率和可能的影响因素。第二阶段研究将作为第一阶段的随访,以评估哮喘及过敏性疾病的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54f5/6019742/eba63c3e9014/00034-2018.01.jpg

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