海洋骨骼：迈向硬组织修复和再生。

Department of Mechanical and Industrial Engineering, University of Dar es Salaam, P.O. Box 35131, Dar es Salaam, Tanzania.

Advanced Tissue Regeneration & Drug Delivery Group, School of Life Sciences, University of Technology Sydney, P.O. Box 123, Broadway, NSW 2007, Australia.

Mar Drugs. 2018 Jul 2;16(7):225. doi: 10.3390/md16070225.

Musculoskeletal disorders in the elderly have significantly increased due to the increase in an ageing population. The treatment of these diseases necessitates surgical procedures, including total joint replacements such as hip and knee joints. Over the years a number of treatment options have been specifically established which are either permanent or use temporary natural materials such as marine skeletons that possess unique architectural structure and chemical composition for the repair and regeneration of bone tissue. This review paper will give an overview of presently used materials and marine structures for hard tissue repair and regeneration, drugs of marine origin and other marine products which show potential for musculoskeletal treatment.

由于人口老龄化的增加，老年人的肌肉骨骼疾病显著增加。这些疾病的治疗需要手术，包括全关节置换，如髋关节和膝关节。多年来，已经确定了许多治疗选择，这些选择要么是永久性的，要么使用临时的天然材料，如具有独特建筑结构和化学成分的海洋骨骼，用于修复和再生骨组织。本文综述了目前用于硬组织修复和再生的材料和海洋结构、海洋来源的药物和其他具有肌肉骨骼治疗潜力的海洋产品。