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重新审视肠道微生物群urolin 代谢类型:鞣花酸的人体代谢主要由衰老决定。

The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging.

机构信息

Laboratory of Food & Health, Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, P.O. Box 164, 30100 Campus de Espinardo, Murcia, Spain.

出版信息

Food Funct. 2018 Aug 15;9(8):4100-4106. doi: 10.1039/c8fo00956b.

Abstract

Understanding individuals' response to dietary bioactives is crucial for personalized nutrition. We report here for the first time in a Caucasian cohort (5-90 years, n = 839) that aging is the main factor that determines the gut microbiota involved in the ellagic acid-ellagitannin metabolism (urolithin metabotypes), with potential consequences for human health.

摘要

了解个体对膳食生物活性物质的反应对于个性化营养至关重要。我们在此首次在白种人队列(5-90 岁,n = 839)中报告,衰老是决定参与鞣花酸-鞣花单宁代谢(尿石素代谢类型)的肠道微生物群的主要因素,这可能对人类健康产生影响。

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