园艺芳香作物精油在埃及北部的有效抗氧化、抗菌和抗癌活性。
Effective antioxidant, antimicrobial and anticancer activities of essential oils of horticultural aromatic crops in northern Egypt.
机构信息
Plant production Department, College of Food and Agriculture Sciences, King Saud University, P.O. Box 2460, Riyadh, 11451, Saudi Arabia.
Floriculture, Ornamental Horticulture and Garden Design Department, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria, Egypt.
出版信息
BMC Complement Altern Med. 2018 Jul 13;18(1):214. doi: 10.1186/s12906-018-2262-1.
BACKGROUND
Identifying ornamental plants as new natural antioxidant and antimicrobial sources is always of great importance for the ornamental and horticultural industries.
METHODS
The antimicrobial activities of leaves and fruits peel essential oils of twelve ornamental and horticultural crops were determined by screening against wide spectrum of fungi and bacteria, and their respective in vitro antioxidant capacity was evaluated. Furthermore, the anticancer activities against several cancer cells, and one normal human cell line (HEK-293) were examined.
RESULTS
Origanum vulgare L. essential oil showed the best antioxidant, antibacterial and anticancer activities compared to screened crops by means of the DPPH and linoleic acid assays for antioxidants, MIC and MBC values for antibacterial activities and IC for antiproliferative activities. Such important activities in O. vulgare was attributed to high pulegone ratio (77.45%) as revealed by the GC/MS assay. Rosmarinus officinallis L. essential oil showed the highest antifungal activities by means of lowest MIC and MFC values which might be attributed to 1, 8-cineole (19.60%), camphor (17.01%) and α-pinene (15.12%).
CONCLUSION
We suggest that oxygenated monoterpenes (i.e. linalool, terpinen-4-ol and pulegone) and monoterpene hydrocarbons play an important role in the essential oil antioxidant, antibacterial, antifungal and anticancer activities of diverse Egyptian ornamental and horticultural crops. Some species showed bioactivities similar to standards compounds and might be suitable for pharmaceutical and food industries.
背景
识别观赏植物作为新的天然抗氧化剂和抗菌来源，对于观赏园艺产业始终具有重要意义。
方法
通过对广谱真菌和细菌的筛选，测定了 12 种观赏园艺作物的叶片和果实皮精油的抗菌活性，并评价了各自的体外抗氧化能力。此外，还检测了几种癌细胞和一种正常人类细胞系（HEK-293）的抗癌活性。
结果
与筛选的作物相比，牛至精油通过 DPPH 和亚油酸测定法对抗氧化剂、MIC 和 MBC 值对细菌活性以及 IC 对增殖活性的测定，表现出最佳的抗氧化、抗菌和抗癌活性。GC/MS 分析表明，这种重要的活性归因于高侧柏酮比例（77.45%）。迷迭香精油通过最低的 MIC 和 MFC 值表现出最高的抗真菌活性，这可能归因于 1,8-桉油醇（19.60%）、樟脑（17.01%）和α-蒎烯（15.12%）。
结论
我们认为，含氧单萜（即芳樟醇、萜品-4-醇和侧柏酮）和单萜烃在不同埃及观赏园艺作物的精油抗氧化、抗菌、抗真菌和抗癌活性中起着重要作用。一些物种表现出与标准化合物相似的生物活性，可能适合制药和食品工业。
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