Department of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden
Department of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden.
Biol Lett. 2018 Jul;14(7). doi: 10.1098/rsbl.2018.0063.
Cardiac oxygenation is achieved via both coronary arterial and luminal venous oxygen supply routes in many fish species. However, the relative importance of these supplies for cardiac and aerobic metabolic performance is not fully understood. Here, we investigated how coronary artery ligation in rainbow trout (), implanted with heart rate loggers, affected cardiorespiratory performance While coronary ligation significantly elevated resting heart rate, the standard metabolic rate was unchanged compared to sham-treated controls. However, coronary ligation reduced the maximum metabolic rate while heart rate remained unchanged following enforced exercise. Thus, coronary ligation reduced metabolic and heart rate scopes by 29% and 74%, respectively. Our findings highlight the importance of coronary oxygen supply for overall cardiorespiratory performance in salmonid fish, and suggest that pathological conditions that impair coronary flow (e.g. coronary arteriosclerosis) constrain the ability of fish to cope with metabolically demanding challenges such as spawning migrations and environmental warming.
心脏的氧合是通过多种鱼类的冠状动脉和管腔静脉氧供应途径来实现的。然而，这些供应对心脏和有氧代谢性能的相对重要性尚不完全清楚。在这里，我们研究了植入心率记录仪的虹鳟鱼（）的冠状动脉结扎如何影响心肺呼吸表现。虽然冠状动脉结扎显著提高了静息心率，但与假手术对照组相比，标准代谢率没有变化。然而，冠状动脉结扎减少了最大代谢率，而在强制运动后心率保持不变。因此，冠状动脉结扎分别减少了代谢和心率范围 29%和 74%。我们的发现强调了冠状氧供应对鲑鱼鱼类整体心肺呼吸表现的重要性，并表明损害冠状动脉血流的病理状况（例如冠状动脉粥样硬化）限制了鱼类应对产卵洄游和环境变暖等代谢需求挑战的能力。
