Beri Kavita
Medical Director, Beri Esthetique: Mind Body Skin Integrative Laser Aesthetics Med Spa. Ocean NJ 07712, USA.
Adjunct Professor, Department of Biomedical Engineering, Rutgers University, New Brusnwick NJ 08854, USA.
Future Sci OA. 2018 Mar 28;4(6):FSO302. doi: 10.4155/fsoa-2017-0117. eCollection 2018 Jul.
Recent advances in our understanding of the function of the skin and its microbiome have shown that there is a strong symbiotic relationship between the microbiota of the skin and its host immune functions. The dysbiosis or imbalance of the microbiome and other factors that have an influence on the surface microbiota can influence keratinocyte regulation and homeostasis as well as the skin barrier function. In this perspective paper, we review the evidence that connects the skin's microbiome and the barrier function of the epidermis and explore the future potential for applying this unique dialogue in developing innovative cosmetics and transdermal drugs for wellbeing and beauty.
我们对皮肤及其微生物群功能的理解最近取得的进展表明，皮肤微生物群与其宿主免疫功能之间存在着紧密的共生关系。微生物群的失调或失衡以及其他影响皮肤表面微生物群的因素会影响角质形成细胞的调节和稳态以及皮肤屏障功能。在这篇观点论文中，我们回顾了将皮肤微生物群与表皮屏障功能联系起来的证据，并探讨了在开发促进健康和美丽的创新化妆品及透皮药物中应用这种独特相互作用的未来潜力。
