Solomon A R, Rasmussen J E, Weiss J S
Arch Dermatol. 1986 Mar;122(3):282-5.
We compared the usefulness of the Tzanck smear to viral culture in patients with varicella and herpes zoster. All 11 patients with early lesions of varicella had a positive Tzanck preparation, while only seven (64%) of 11 had a positive culture. Twelve (80%) of 15 patients with zoster had a positive Tzanck preparation, while only nine (60%) of 15 had a positive culture. The predominance of the Tzanck yield over the culture is probably due to the increased difficulty in isolation of the varicella zoster virus. These results suggest that the Tzanck preparation is a valuable tool in the diagnosis of patients with varicella and zoster and offers a much more immediate answer than does viral culture, which often takes one to two weeks. These results contrast with those of our previous study of the Tzanck preparation and herpes simplex, in which the viral culture was more accurate than the Tzanck preparation.
我们比较了Tzanck涂片法与病毒培养法在水痘和带状疱疹患者中的效用。所有11例水痘早期皮损患者的Tzanck涂片检查均呈阳性，而11例中只有7例（64%）病毒培养呈阳性。15例带状疱疹患者中有12例（80%）Tzanck涂片检查呈阳性，而15例中只有9例（60%）病毒培养呈阳性。Tzanck涂片法阳性率高于病毒培养法，这可能是由于水痘带状疱疹病毒的分离难度增加所致。这些结果表明，Tzanck涂片检查是诊断水痘和带状疱疹患者的一项有价值的工具，它比通常需要1至2周时间的病毒培养能更快给出结果。这些结果与我们之前关于Tzanck涂片法和单纯疱疹的研究结果形成对比，在该研究中病毒培养比Tzanck涂片法更准确。
