Department of Bioengineering, The University of Texas at Dallas, Richardson, TX.
Private practice of periodontics, Dallas, TX.
J Periodontol. 2019 Jan;90(1):72-81. doi: 10.1002/JPER.18-0110. Epub 2018 Sep 4.
Titanium (Ti) dominates as the material of choice for dental implant systems. Recently, titanium-zirconium alloy (TiZr) and zirconia (ZrO ) have emerged as alternative materials due to higher mechanical strength and lower corrosion susceptibility. Oral pathogenic bacteria can colonize Ti surfaces, leading to surface degradation, which has yet to be investigated on TiZr and ZrO . The aim of this study was to compare in vitro oral bacterial adhesion and subsequent surface degradation on commercial Ti, TiZr, and ZrO implants.
Ti, TiZr, and ZrO implants with sandblasted, acid-etched (SLA) surfaces in addition to modified SLA-treated (modSLA) Ti implants (n = 3) were immersed for 30 consecutive days in Streptococcus polyculture. Post-immersion, adherent bacterial count was quantified. Optical microscopy was used to assess qualitative degradation and score Ti-based implants based on degree of surface damage while electrochemical testing quantified corrosion behavior. Analysis of variance followed by post-hoc Tukey test was used to statistically compare quantitative results (α = 0.05).
Ti-SLA, Ti-modSLA, and TiZr-SLA implants exhibited localized features characteristic of corrosion attack while ZrO -SLA implants experienced minimal changes in surface morphology as compared to non-immersed control. Corrosion features were more numerous on Ti-modSLA implants but smaller in size as compared with those on Ti-SLA and TiZr-SLA implants. No significant differences in corrosion resistance (polarization resistance and corrosion rate) were observed between Ti-SLA, Ti-modSLA, and TiZr-SLA implants.
TiZr and ZrO dental implant surfaces were not more susceptible to colonization and surface degradation by oral Streptococcus species than commercially pure Ti implants.
钛（Ti）是牙科植入系统首选材料。最近，钛锆合金（TiZr）和氧化锆（ZrO）因其更高的机械强度和更低的腐蚀性而成为替代材料。口腔致病菌可在 Ti 表面定植，导致表面降解，但尚未对 TiZr 和 ZrO 进行研究。本研究旨在比较商用 Ti、TiZr 和 ZrO 植入物表面体外口腔细菌黏附和随后的表面降解。
采用喷砂酸蚀（SLA）表面的 Ti、TiZr 和 ZrO 植入物，以及改良 SLA 处理的 Ti 植入物（n=3），连续 30 天浸入链球菌混合培养物中。浸泡后，定量检测附着细菌数量。光学显微镜用于评估定性降解，并根据表面损伤程度对 Ti 基植入物进行评分，电化学测试则量化腐蚀行为。采用方差分析，随后进行 Tukey 事后检验，对定量结果进行统计学比较（α=0.05）。
Ti-SLA、Ti-modSLA 和 TiZr-SLA 植入物表现出局部特征，具有腐蚀攻击特征，而 ZrO-SLA 植入物与未浸泡对照相比，表面形态变化最小。与 Ti-SLA 和 TiZr-SLA 植入物相比，Ti-modSLA 植入物的腐蚀特征更多，但尺寸更小。Ti-SLA、Ti-modSLA 和 TiZr-SLA 植入物的耐腐蚀性（极化电阻和腐蚀速率）无显著差异。
与商用纯 Ti 植入物相比，TiZr 和 ZrO 牙科植入物表面不易被口腔链球菌定植和表面降解。
