School of Chemistry, Sun Yat-sen University, Guangzhou 510275, China.
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Molecules. 2018 Aug 21;23(9):2095. doi: 10.3390/molecules23092095.
Linear triquinane sesquiterpenoids represent an important class of natural products. Most of these compounds were isolated from fungi, sponges, and soft corals, and many of them displayed a wide range of biological activities. On account of their structural diversity and complexity, linear triquinane sesquiterpenoids present new challenges for chemical structure identification and total synthesis. 118 linear triquinane sesquiterpenoids were classified into 8 types, named types I⁻VIII, based on the carbon skeleton and the position of carbon substituents. Their isolation, structure elucidations, biological activities, and chemical synthesis were reviewed. This paper cited 102 articles from 1947 to 2018.
线性三尖杉烷倍半萜是一类重要的天然产物。这些化合物大多从真菌、海绵和软珊瑚中分离得到，其中许多具有广泛的生物活性。由于其结构的多样性和复杂性，线性三尖杉烷倍半萜类化合物对化学结构鉴定和全合成提出了新的挑战。根据碳骨架和碳取代基的位置，将 118 种线性三尖杉烷倍半萜分为 8 种类型，分别命名为 I⁻VIII 型。综述了它们的分离、结构鉴定、生物活性和化学合成。本文引用了 1947 年至 2018 年的 102 篇文章。
