• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

粪便微生物群移植作为根除多重耐药微生物的一种潜在方法。

Fecal microbiota transplantation as a potential way to eradicate multiresistant microorganisms.

作者信息

Dias Cátia, Pipa Sara, Duarte-Ribeiro Filipa, Mota Margarida

机构信息

Department of Internal Medicine, Centro Hospitalar de Vila Nova de Gaia/Espinho, Portugal.

出版信息

IDCases. 2018 Aug 13;13:e00432. doi: 10.1016/j.idcr.2018.e00432. eCollection 2018.

DOI:10.1016/j.idcr.2018.e00432
PMID:30140609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6105750/
Abstract

Multiresistant microorganism infection often can produce a life-threatening situation. We report two cases in which fecal microbiota transplantation used for the treatment of recurrent infection were effective in eradicating colonization by carbapenemase-producing . The presented cases illustrate the potential benefit of fecal microbiota transplantation in resolution of asymptomatic carrier states of multiresistant microorganisms, suggesting the need for further investigations with a view to their applicability in this area.

摘要

多重耐药微生物感染往往会导致危及生命的情况。我们报告了两例使用粪便微生物群移植治疗复发性感染的病例，这些治疗在根除产碳青霉烯酶菌的定植方面是有效的。所展示的病例说明了粪便微生物群移植在解决多重耐药微生物无症状携带状态方面的潜在益处，这表明有必要进一步研究其在该领域的适用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f668/6105750/043d337e20f0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f668/6105750/7703c32fcbe8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f668/6105750/043d337e20f0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f668/6105750/7703c32fcbe8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f668/6105750/043d337e20f0/gr2.jpg

相似文献

1
Fecal microbiota transplantation as a potential way to eradicate multiresistant microorganisms.粪便微生物群移植作为根除多重耐药微生物的一种潜在方法。
IDCases. 2018 Aug 13;13:e00432. doi: 10.1016/j.idcr.2018.e00432. eCollection 2018.
2
Gut eradication of VIM-1 producing ST9 Klebsiella oxytoca after fecal microbiota transplantation for diarrhea caused by a Clostridium difficile hypervirulent R027 strain.在因艰难梭菌高毒力R027菌株引起的腹泻进行粪便微生物群移植后，肠道中产生VIM-1的ST9产酸克雷伯菌被清除。
Diagn Microbiol Infect Dis. 2016 Dec;86(4):470-471. doi: 10.1016/j.diagmicrobio.2016.09.004. Epub 2016 Sep 16.
3
Antimicrobial Use, Human Gut Microbiota and Clostridium difficile Colonization and Infection.抗菌药物的使用、人类肠道微生物群与艰难梭菌定植和感染。
Antibiotics (Basel). 2015 Jul 3;4(3):230-53. doi: 10.3390/antibiotics4030230.
4
Non-invasive fecal microbiota transplantation for recurrent Clostridium difficile infection in a patient presenting with hypertensive disorder post interventionem.干预后出现高血压疾病的患者复发性艰难梭菌感染的非侵入性粪便微生物群移植
Z Gastroenterol. 2016 Oct;54(10):1143-1146. doi: 10.1055/s-0042-110795. Epub 2016 Sep 19.
5
Fecal microbiota transplantation in the treatment of Clostridium difficile infections.粪便微生物群移植治疗艰难梭菌感染。
Am J Med. 2014 Jun;127(6):479-83. doi: 10.1016/j.amjmed.2014.02.017. Epub 2014 Feb 26.
6
[Fecal microbiota transplantation in recurrent Clostridium difficile infections. Framework and pharmaceutical preparation aspects].[复发性艰难梭菌感染中的粪便微生物群移植。框架与药物制剂方面]
Ann Pharm Fr. 2015 Sep;73(5):323-31. doi: 10.1016/j.pharma.2015.02.004. Epub 2015 Mar 29.
7
[Experience with fecal transplantation in the treatment of Clostridium difficile infection].[粪便移植治疗艰难梭菌感染的经验]
Orv Hetil. 2014 Nov 2;155(44):1758-62. doi: 10.1556/OH.2014.30020.
8
Metagenomic Characterization of Gut Microbiota of Carriers of Extended-Spectrum Beta-Lactamase or Carbapenemase-Producing Enterobacteriaceae Following Treatment with Oral Antibiotics and Fecal Microbiota Transplantation: Results from a Multicenter Randomized Trial.口服抗生素和粪便微生物群移植治疗后产超广谱β-内酰胺酶或碳青霉烯酶肠杆菌科细菌携带者肠道微生物群的宏基因组特征：一项多中心随机试验的结果
Microorganisms. 2020 Jun 23;8(6):941. doi: 10.3390/microorganisms8060941.
9
Is frozen fecal microbiota transplantation as effective as fresh fecal microbiota transplantation in patients with recurrent or refractory Clostridium difficile infection: A meta-analysis?在复发性或难治性艰难梭菌感染患者中，冷冻粪便微生物群移植与新鲜粪便微生物群移植的效果是否相同：一项荟萃分析？
Diagn Microbiol Infect Dis. 2017 Aug;88(4):322-329. doi: 10.1016/j.diagmicrobio.2017.05.007. Epub 2017 May 18.
10
Fecal microbiota transplantation in recurrent Clostridium difficile infection in a patient with concomitant inflammatory bowel disease.粪便微生物群移植治疗合并炎症性肠病的复发性艰难梭菌感染患者
Rev Esp Enferm Dig. 2017 Jun;109(6):473-476. doi: 10.17235/reed.2017.4819/2016.

引用本文的文献

1
The potential utility of fecal (or intestinal) microbiota transplantation in controlling infectious diseases.粪便（或肠道）微生物群移植在控制传染病中的潜在应用。
Gut Microbes. 2022 Jan-Dec;14(1):2038856. doi: 10.1080/19490976.2022.2038856.
2
The Intestinal Microbiota as a Reservoir and a Therapeutic Target to Fight Multi-Drug-Resistant Bacteria: A Narrative Review of the Literature.肠道微生物群作为对抗多重耐药菌的储存库和治疗靶点：文献综述
Infect Dis Ther. 2019 Dec;8(4):469-482. doi: 10.1007/s40121-019-00272-7. Epub 2019 Oct 25.
3
Efficacy and safety of fecal microbiota transplantation for decolonization of intestinal multidrug-resistant microorganism carriage: beyond infection.

本文引用的文献

1
Is faecal microbiota transplantation an option to eradicate highly drug-resistant enteric bacteria carriage?粪便微生物群移植是根除高度耐药性肠道细菌携带的一种选择吗？
J Hosp Infect. 2017 Apr;95(4):433-437. doi: 10.1016/j.jhin.2017.02.001. Epub 2017 Feb 6.
2
Antimicrobial Resistance.抗菌药物耐药性
JAMA. 2016 Sep 20;316(11):1193-1204. doi: 10.1001/jama.2016.11764.
3
Fecal microbiota transplantation and successful resolution of multidrug-resistant-organism colonization.粪便微生物群移植与多重耐药菌定植的成功清除
粪便微生物群移植在肠道多重耐药菌定植中的疗效和安全性：超越感染。
Ann Med. 2019 Nov-Dec;51(7-8):379-389. doi: 10.1080/07853890.2019.1662477. Epub 2019 Sep 13.
4
Microbiome predictors of dysbiosis and VRE decolonization in patients with recurrent infections in a multi-center retrospective study.一项多中心回顾性研究中复发性感染患者菌群失调及耐万古霉素肠球菌去定植的微生物组预测指标
AIMS Microbiol. 2019 Jan 17;5(1):1-18. doi: 10.3934/microbiol.2019.1.1. eCollection 2019.
J Clin Microbiol. 2015 Jun;53(6):1986-9. doi: 10.1128/JCM.00820-15. Epub 2015 Apr 15.
4
Microbiota-mediated colonization resistance against intestinal pathogens.微生物群介导的定植抵抗肠道病原体。
Nat Rev Immunol. 2013 Nov;13(11):790-801. doi: 10.1038/nri3535. Epub 2013 Oct 7.
5
Control of pathogens and pathobionts by the gut microbiota.肠道微生物群对病原体和条件致病菌的控制。
Nat Immunol. 2013 Jul;14(7):685-90. doi: 10.1038/ni.2608.
6
Fecal microbiota transplantation for Clostridium difficile infection: systematic review and meta-analysis.粪菌移植治疗艰难梭菌感染：系统评价和荟萃分析。
Am J Gastroenterol. 2013 Apr;108(4):500-8. doi: 10.1038/ajg.2013.59. Epub 2013 Mar 19.
7
Duodenal infusion of donor feces for recurrent Clostridium difficile.经十二指肠输注供体粪便治疗复发性艰难梭菌感染。
N Engl J Med. 2013 Jan 31;368(5):407-15. doi: 10.1056/NEJMoa1205037. Epub 2013 Jan 16.
8
Predictors of mortality in patients with infections due to multi-drug resistant Gram negative bacteria: the study, the patient, the bug or the drug?多重耐药革兰氏阴性菌感染患者死亡的预测因素：研究、患者、细菌还是药物？
J Infect. 2013 May;66(5):401-14. doi: 10.1016/j.jinf.2012.10.028. Epub 2012 Nov 6.
9
Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation.肠定植与异基因造血干细胞移植患者发生菌血症的风险。
Clin Infect Dis. 2012 Oct;55(7):905-14. doi: 10.1093/cid/cis580. Epub 2012 Jun 20.
10
Decontamination of cephalosporin-resistant Enterobacteriaceae during selective digestive tract decontamination in intensive care units.在重症监护病房进行选择性消化道去污染时对抗头孢菌素的肠杆菌科的去污染。
J Antimicrob Chemother. 2012 Sep;67(9):2250-3. doi: 10.1093/jac/dks187. Epub 2012 May 29.