Maarse F, Jager D-H-J, Forouzanfar T, Wolff J, Brand H-S
Department of Oral and Maxillofacial Surgery and Oral Pathology, VU University Medical Center, P.O. Box 7057 1007 MB Amsterdam, The Netherlands,
Med Oral Patol Oral Cir Bucal. 2018 Sep 1;23(5):e545-e551. doi: 10.4317/medoral.22545.
To analyze the prevalence and location of tooth loss in Sjögren's syndrome (SS) patients and compare them with an age- and gender-matched control group.
Dental charts and x-rays of 108 (SS) patients were retrieved from an academic dental center and special care dentistry department. For each SS patient, an age- and gender-matched non-SS patient was randomly selected. Medication, number of extractions and date and location of extractions were assessed. Differences between SS and non-SS patients were analyzed using Mann-Whitney U tests, Chi-square tests and Fisher's exact tests.
Significantly more SS patients were edentulous compared to the non-SS group (14.8% versus 1.9%, p = 0.001). SS patients had a 61% higher risk to have experienced one or more extractions than control patients. In the SS group, there was a non-significant tendency for more maxillary teeth to have been extracted than mandibular teeth (42:34). In the control group, the number of extractions in the maxilla and mandible were comparable (21:20). When divided into sextants, the number of SS patients with one or more extractions was significantly higher than for non-SS patients for each sextant (p = 0.001 to p = 0.032). The largest difference in the proportion of patients with one or more extractions between the SS and non-SS patients occurred in the upper anterior sextant (3.4 times more frequent).
SS patients are more prone to experience dental extractions compared to patients without SS. It could be speculated that this is related to a decreased salivary secretion.
分析干燥综合征（SS）患者牙齿缺失的患病率及部位，并与年龄和性别匹配的对照组进行比较。
从一家学术牙科中心和特殊护理牙科部门检索了108例SS患者的牙科图表和X光片。为每位SS患者随机选择一名年龄和性别匹配的非SS患者。评估用药情况、拔牙数量以及拔牙日期和部位。使用曼-惠特尼U检验、卡方检验和费舍尔精确检验分析SS患者与非SS患者之间的差异。
与非SS组相比，SS患者无牙的比例明显更高（14.8%对1.9%，p = 0.001）。SS患者经历一次或多次拔牙的风险比对照患者高61%。在SS组中，上颌牙被拔除的数量比下颌牙略多，但差异无统计学意义（42:34）。在对照组中，上颌和下颌的拔牙数量相当（21:20）。按牙弓分区分析，每个牙弓分区中，有一次或多次拔牙的SS患者数量均显著高于非SS患者（p = 0.001至p = 0.032）。SS患者与非SS患者中，有一次或多次拔牙的患者比例差异最大的是上前牙弓分区（前者是后者的3.4倍）。
与非SS患者相比，SS患者更容易拔牙。据推测，这可能与唾液分泌减少有关。
