Salceanu Silvia Olivia, Raman Vasant
University hospitals of Plymouth, Royal Eye Infirmary, Derriford, Plymouth, UK.
BMJ Case Rep. 2018 Aug 27;2018:bcr-2017-222864. doi: 10.1136/bcr-2017-222864.
Chikungunya is a systemic viral disease transmitted to humans by infected mosquitoes in endemic areas of Africa, Asia and more recently in the Americas. Chikungunya infection produces a sudden onset of fever, joint pains and erythematous skin eruption. A plethora of ocular manifestations have been described ranging from a non-specific conjunctivitis to exudative retinal detachment. Ocular chikungunya seems to respond well to corticosteroid therapy, and outcomes are usually better if treated early. Our patient acquired this infection on a travel to Mexico jungle. This was confirmed by ReverseTranscriptase-PCR test once she returned to the UK. The peculiarity of the case is the inordinate delay of almost a year in the onset of eye symptoms, from acquiring the viral infection. The ocular inflammation responded to systemic corticosteroid therapy with a favourable visual outcome. She developed a recurrence many months later which again responded well to a course of oral steroids.
基孔肯雅热是一种由受感染蚊子传播给人类的全身性病毒疾病，在非洲、亚洲的流行地区以及最近在美洲均有传播。基孔肯雅热感染会突然引发发热、关节疼痛和皮肤红斑疹。已经描述了大量眼部表现，从非特异性结膜炎到渗出性视网膜脱离。眼部基孔肯雅热似乎对皮质类固醇疗法反应良好，如果早期治疗，通常预后更好。我们的患者在前往墨西哥丛林旅行时感染了这种疾病。她返回英国后，逆转录聚合酶链反应检测证实了这一点。该病例的独特之处在于，从感染病毒到出现眼部症状几乎延迟了一年时间。眼部炎症对全身性皮质类固醇疗法有反应，视力预后良好。几个月后她病情复发，再次接受口服类固醇疗程治疗后反应良好。
