从感染的小家鼠中分离出的胡宁病毒抗原变异体。简报。
Antigenic variants of Junín virus isolated from infected Calomys musculinus. Brief report.
作者信息
Alché L E, Coto C E
出版信息
Arch Virol. 1986;90(3-4):343-8. doi: 10.1007/BF01317382.
PMID:3015087
Abstract
Junín virus establishes a long-term persistent infection in its natural host, Calomys musculinus. Virus recovered from blood of infected animals from 14 to 61 days p.i. behaved antigenically distinct to parental virus, as shown by cross neutralization assays. The emergence of antigenic viral variants occurs during both the acute and persistent state of infection.
摘要
胡宁病毒在其天然宿主小家鼠中建立长期持续性感染。在感染后14至61天从受感染动物血液中分离出的病毒，经交叉中和试验表明，其抗原性与亲代病毒不同。抗原性病毒变体在感染的急性期和持续期均会出现。
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