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Polarization Variability in Age-related Macular Degeneration.年龄相关性黄斑变性中的偏振变异性
Optom Vis Sci. 2018 Apr;95(4):277-291. doi: 10.1097/OPX.0000000000001197.
2
Measuring polarization changes in the human outer retina with polarization-sensitive optical coherence tomography.使用偏振敏感光学相干断层扫描测量人眼外层视网膜的偏振变化。
J Biophotonics. 2018 May;11(5):e201700134. doi: 10.1002/jbio.201700134. Epub 2018 Feb 26.
3
Intraocular light scatter, reflections, fluorescence and absorption: what we see in the slit lamp.眼内光散射、反射、荧光和吸收:我们在裂隙灯中看到的情况。
Ophthalmic Physiol Opt. 2018 Jan;38(1):6-25. doi: 10.1111/opo.12426.
4
Evaluation of intraretinal migration of retinal pigment epithelial cells in age-related macular degeneration using polarimetric imaging.应用偏光成像评估年龄相关性黄斑变性的视网膜色素上皮细胞的视网膜内迁移。
Sci Rep. 2017 Jun 9;7(1):3150. doi: 10.1038/s41598-017-03529-8.
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Retinal Remodeling and Metabolic Alterations in Human AMD.人类年龄相关性黄斑变性中的视网膜重塑与代谢改变
Front Cell Neurosci. 2016 Apr 28;10:103. doi: 10.3389/fncel.2016.00103. eCollection 2016.
6
Henle fiber layer phase retardation changes associated with age-related macular degeneration.与年龄相关性黄斑变性相关的Henle纤维层相位延迟变化。
Invest Ophthalmol Vis Sci. 2014 Dec 18;56(1):284-90. doi: 10.1167/iovs.14-14459.
7
Improved eye-fixation detection using polarization-modulated retinal birefringence scanning, immune to corneal birefringence.利用偏振调制视网膜双折射扫描改进眼注视检测,不受角膜双折射影响。
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8
Cone photoreceptor packing density and the outer nuclear layer thickness in healthy subjects.健康受试者的圆锥细胞光感受器密度和外核层厚度。
Invest Ophthalmol Vis Sci. 2012 Jun 14;53(7):3545-53. doi: 10.1167/iovs.11-8694.
9
Foveal localization in non-exudative AMD using scanning laser polarimetry.使用扫描激光偏振仪对非渗出性年龄相关性黄斑变性进行黄斑中心凹定位
Optom Vis Sci. 2012 May;89(5):667-77. doi: 10.1097/OPX.0b013e31824eeb25.
10
Foveal phase retardation changes associated with normal aging.与正常衰老相关的黄斑中心凹相位延迟变化。
Vision Res. 2011 Nov;51(21-22):2263-72. doi: 10.1016/j.visres.2011.08.017. Epub 2011 Aug 27.

近红外偏振成像与正常衰老相关的变化。

Near-infrared polarimetric imaging and changes associated with normative aging.

作者信息

Papay Joel A, Elsner Ann E

出版信息

J Opt Soc Am A Opt Image Sci Vis. 2018 Sep 1;35(9):1487-1495. doi: 10.1364/JOSAA.35.001487.

DOI:10.1364/JOSAA.35.001487
PMID:30183002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6640646/
Abstract

With aging, the human retina undergoes cell death and additional structural changes that can increase scattered light. We quantified the effect of normative aging on multiply scattered light returning from the human fundus. As expected, there was an increase of multiply scattered light associated with aging, and this is consistent with the histological changes that occur in the fundus of individuals before developing age-related macular degeneration. This increase in scattered light with aging cannot be attributed to retinal reflectivity, anterior segment scatter, or pupil diameter.

摘要

随着年龄的增长,人类视网膜会经历细胞死亡以及其他结构变化,这些变化会增加散射光。我们量化了正常衰老对从人眼底返回的多次散射光的影响。正如预期的那样,与衰老相关的多次散射光有所增加,这与在发生年龄相关性黄斑变性之前个体眼底发生的组织学变化是一致的。这种随年龄增长而增加的散射光不能归因于视网膜反射率、眼前节散射或瞳孔直径。