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1
Nucleotide sequence of the yeast cell division cycle start genes CDC28, CDC36, CDC37, and CDC39, and a structural analysis of the predicted products.酵母细胞分裂周期起始基因CDC28、CDC36、CDC37和CDC39的核苷酸序列，以及预测产物的结构分析。
Nucleic Acids Res. 1986 Aug 26;14(16):6681-97. doi: 10.1093/nar/14.16.6681.
2
Isolation and transcriptional characterization of three genes which function at start, the controlling event of the Saccharomyces cerevisiae cell division cycle: CDC36, CDC37, and CDC39.酿酒酵母细胞分裂周期的控制事件——起始阶段发挥作用的三个基因（CDC36、CDC37和CDC39）的分离及转录特征分析
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3
Mutations in cell division cycle genes CDC36 and CDC39 activate the Saccharomyces cerevisiae mating pheromone response pathway.细胞分裂周期基因CDC36和CDC39的突变激活酿酒酵母交配信息素反应途径。
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Yeast regulatory gene PPR1. I. Nucleotide sequence, restriction map and codon usage.酵母调控基因PPR1。I. 核苷酸序列、限制性图谱及密码子使用情况。
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CDC36 and CDC39 are negative elements in the signal transduction pathway of yeast.CDC36和CDC39是酵母信号转导途径中的负向元件。
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Mating-defective ste mutations are suppressed by cell division cycle start mutations in Saccharomyces cerevisiae.在酿酒酵母中，交配缺陷型ste突变可被细胞分裂周期起始突变所抑制。
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A relationship between the yeast cell cycle genes CDC4 and CDC36 and the ets sequence of oncogenic virus E26.酵母细胞周期基因CDC4和CDC36与致癌病毒E26的ets序列之间的关系。
Nature. 1984;309(5968):556-8. doi: 10.1038/309556a0.
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The RAD2 gene of Saccharomyces cerevisiae: nucleotide sequence and transcript mapping.酿酒酵母的RAD2基因：核苷酸序列与转录图谱
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Nucleotide sequence of the Saccharomyces cerevisiae arginase gene (CAR1) and its transcription under various physiological conditions.酿酒酵母精氨酸酶基因（CAR1）的核苷酸序列及其在不同生理条件下的转录情况。
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"Start" mutants of Saccharomyces cerevisiae are suppressed in carbon catabolite-derepressing medium.酿酒酵母的“起始”突变体在碳分解代谢物去阻遏培养基中受到抑制。
J Bacteriol. 1982 Aug;151(2):1059-61. doi: 10.1128/jb.151.2.1059-1061.1982.

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Exploring the Functional Complementation between Grp94 and Hsp90.探索葡萄糖调节蛋白94与热休克蛋白90之间的功能互补作用。
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Fission yeast Cdc37 is required for multiple cell cycle functions.裂殖酵母Cdc37是多种细胞周期功能所必需的。
Mol Genet Genomics. 2004 Feb;271(1):82-90. doi: 10.1007/s00438-003-0958-4. Epub 2003 Dec 3.
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Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase.鉴定Cdc37作为应激反应性丝裂原活化蛋白激酶的新型调节因子。
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Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes.不同的酵母Not2功能结构域与Gcn5组蛋白乙酰转移酶和Ccr4转录调控复合物成分的关联。
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The yeast CDC37 gene interacts with MPS1 and is required for proper execution of spindle pole body duplication.酵母CDC37基因与MPS1相互作用，是纺锤极体复制正常进行所必需的。
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CDC37 is required for p60v-src activity in yeast.CDC37是酵母中p60v-src活性所必需的。
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Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins.蛋白激酶Cdc28与G1期和有丝分裂周期蛋白的结合需要Cdc37。
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Pachytene arrest and other meiotic effects of the start mutations in Saccharomyces cerevisiae.酿酒酵母起始突变的粗线期停滞及其他减数分裂效应
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10
Overlapping reading frames at the LYS5 locus in the yeast Yarrowia lipolytica.解脂耶氏酵母中LYS5基因座的重叠阅读框。
Mol Cell Biol. 1990 Sep;10(9):4795-806. doi: 10.1128/mcb.10.9.4795-4806.1990.

本文引用的文献

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Genetic Control of the Cell Division Cycle in Yeast: V. Genetic Analysis of cdc Mutants.酵母细胞分裂周期的遗传控制：V. cdc 突变体的遗传分析。
Genetics. 1973 Jun;74(2):267-86. doi: 10.1093/genetics/74.2.267.
2
Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes.侧翼核苷酸在真核生物核糖体识别AUG起始密码子中的可能作用。
Nucleic Acids Res. 1981 Oct 24;9(20):5233-52. doi: 10.1093/nar/9.20.5233.
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A simple method for displaying the hydropathic character of a protein.一种展示蛋白质亲水性特征的简单方法。
J Mol Biol. 1982 May 5;157(1):105-32. doi: 10.1016/0022-2836(82)90515-0.
4
The role of S. cerevisiae cell division cycle genes in nuclear fusion.酿酒酵母细胞分裂周期基因在核融合中的作用。
Genetics. 1982 Feb;100(2):175-84. doi: 10.1093/genetics/100.2.175.
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Codon selection in yeast.酵母中的密码子选择
J Biol Chem. 1982 Mar 25;257(6):3026-31.
6
The effect of temperature-sensitive RNA mutants on the transcription products from cloned ribosomal protein genes of yeast.温度敏感型RNA突变体对酵母核糖体蛋白基因克隆转录产物的影响。
Cell. 1981 Jun;24(3):679-86. doi: 10.1016/0092-8674(81)90094-5.
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The selection of S. cerevisiae mutants defective in the start event of cell division.酿酒酵母中在细胞分裂起始事件中存在缺陷的突变体的筛选。
Genetics. 1980 Jul;95(3):561-77. doi: 10.1093/genetics/95.3.561.
8
Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence.伴清蛋白基因的特异性体外转录因T-A-T-A盒同源序列中的单点突变而急剧减少。
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7024-8. doi: 10.1073/pnas.77.12.7024.
9
Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.通过对体内特定缺失突变体的研究鉴定H2A组蛋白基因前奏序列中的调控序列。
Proc Natl Acad Sci U S A. 1980 Mar;77(3):1432-6. doi: 10.1073/pnas.77.3.1432.
10
A relationship between the yeast cell cycle genes CDC4 and CDC36 and the ets sequence of oncogenic virus E26.酵母细胞周期基因CDC4和CDC36与致癌病毒E26的ets序列之间的关系。
Nature. 1984;309(5968):556-8. doi: 10.1038/309556a0.

酵母细胞分裂周期起始基因CDC28、CDC36、CDC37和CDC39的核苷酸序列，以及预测产物的结构分析。

Nucleotide sequence of the yeast cell division cycle start genes CDC28, CDC36, CDC37, and CDC39, and a structural analysis of the predicted products.

作者信息

Ferguson J, Ho J Y, Peterson T A, Reed S I

出版信息

Nucleic Acids Res. 1986 Aug 26;14(16):6681-97. doi: 10.1093/nar/14.16.6681.

DOI:10.1093/nar/14.16.6681
PMID:3018676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC311673/
Abstract

The nucleotide sequences of the yeast cell division cycle start genes CDC36, CDC37, and CDC39 are presented. An open reading frame corresponding in size and mapped position to the mRNA for each gene was revealed. These sequences, as well as that of the CDC28 gene, were analyzed for the presence of consensus sequences postulated to be transcriptional or translational signals, or to be involved in mRNA processing. In addition, the predicted protein products of the four genes were subjected to a number of structural and statistical analyses including codon usage bias analysis, secondary structure analysis and hydropathicity analysis.

摘要

本文呈现了酵母细胞分裂周期起始基因CDC36、CDC37和CDC39的核苷酸序列。发现了一个与每个基因的mRNA大小和定位位置相对应的开放阅读框。对这些序列以及CDC28基因的序列进行了分析，以寻找假定为转录或翻译信号、或参与mRNA加工的共有序列。此外，对这四个基因预测的蛋白质产物进行了多项结构和统计分析，包括密码子使用偏好分析、二级结构分析和亲水性分析。