Quoc Johann Bui, Vang Aurélie, Evrard Laurence
Department of Dentistry, Oral and Maxillofacial Surgery, Orthodontics, Stomatology, Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium.
Open Dent J. 2018 Jul 31;12:529-545. doi: 10.2174/1874210601812010529. eCollection 2018.
The aim of our study was to compare peri-implant bone loss at implants placed in alveolar sockets filled with a particulate allogenous bone graft (DFDBA 300-500 µm) and platelet concentrates at implants placed in the native bone.
A retrospective clinical study was performed. A total of 84 patients were included with 247 implants for the restoration of mono and pluri-radicular teeth: 169 implants in native bone and 78 in socket-grafted bone. The peri-implant bone loss was measured by 2 independent operators at 6 and 12 months.
The overall mesial and distal peri-implant bone losses were 0.9 ± 0.7 mm and 0.9 ± 0.8 mm at 6 months, respectively, and 1 ± 0.65 mm and 1.2 ± 0.9 mm at 12 months, respectively. In the tested group, the bone loss was 0.8 ± 0.8 mm at 6 months and 1.2 ± 0.9 mm at 12 months. In the control group, the bone loss was 1.0 ± 0.7 mm at 6 months and 0.95 ± 0.6 mm at 12 months. There were no statistically significant differences in bone loss between the two groups. Taking both groups together, there were no statistically significant difference in bone loss between patients with or without histories of periodontitis, but there was a statistically significant difference in bone loss between the mandible and maxilla as well as between unitary and total edentations and between partially and total edentulous patients.
At 6 and 12 months, the peri-implant bone loss in sockets preserved with DFDBA and platelet concentrates was similar to the peri-implant bone loss in native bone.
本研究的目的是比较植入充满颗粒状同种异体骨移植物（300 - 500 µm 的脱矿冻干骨）的牙槽窝内的种植体周围骨吸收情况，以及植入天然骨内的种植体周围骨吸收情况，并比较同时使用血小板浓缩物时的差异。
进行了一项回顾性临床研究。共纳入 84 例患者，植入 247 颗种植体用于单根牙和多根牙的修复：169 颗种植体植入天然骨，78 颗植入牙槽窝移植骨。由 2 名独立操作人员在 6 个月和 12 个月时测量种植体周围骨吸收情况。
整体而言，种植体近中及远中周围骨吸收在 6 个月时分别为 0.9±0.7 mm 和 0.9±0.8 mm，在 12 个月时分别为 1±0.65 mm 和 1.2±0.9 mm。在测试组中，6 个月时骨吸收为 0.8±0.8 mm，12 个月时为 1.2±0.9 mm。在对照组中，6 个月时骨吸收为 1.0±0.7 mm，12 个月时为 0.95±0.6 mm。两组之间的骨吸收无统计学显著差异。综合两组来看，有或无牙周炎病史的患者之间骨吸收无统计学显著差异，但在下颌骨与上颌骨之间、单牙缺失与全牙缺失之间以及部分牙缺失与全牙缺失患者之间骨吸收存在统计学显著差异。
在 6 个月和 12 个月时，用脱矿冻干骨和血小板浓缩物保存的牙槽窝内种植体周围骨吸收与天然骨内种植体周围骨吸收相似。
