Basset F, Soler P, Jaurand M C, Bignon J
Thorax. 1977 Jun;32(3):303-6. doi: 10.1136/thx.32.3.303.
Fibreoptic broncho-alveolar lavage was used in four patients; the diagnosis of histiocytosis X had been established by lung biopsy in three and was suggested on clinical grounds in the remaining patient. Characteristic cells with an ultrastructural cytoplasmic marker (X body) were found in the washes of all four patients. In the patient without biopsy confirmation, the findings in the broncho-aleolar washes supplied the corroborating evidence for the diagnosis. From this preliminary study the technique seems able to provide a diagnosis in pulmonary histiocytosis X without the need for an open lung biopsy.
对4例患者进行了纤维支气管镜肺泡灌洗；3例通过肺活检确诊为组织细胞增多症X，其余1例根据临床症状推测为此病。在所有4例患者的灌洗物中均发现了具有超微结构细胞质标记物（X小体）的特征性细胞。在未进行活检确诊的患者中，支气管肺泡灌洗结果为诊断提供了确证依据。从这项初步研究来看，该技术似乎能够在无需开胸肺活检的情况下对肺组织细胞增多症X作出诊断。
